Results 161 to 170 of about 4,022 (258)

Assessing Extracellular Vesicle Proteins as Predictive Biomarkers for Developing Type 1 Diabetes

PROTEOMICS, EarlyView.
ABSTRACT Plasma extracellular vesicles (EVs) are considered excellent sources for biomarker discovery since they carry signatures of their cellular origin and disease processes. In this paper, we evaluate the potential of plasma EV proteomics analysis for identifying predictive biomarkers of developing type 1 diabetes (T1D), which results from ...
Panshak P. Dakup, Lisa M. Bramer, Athena Schepmoes, Ivo Diaz Ludovico, Javier Flores, Raghavendra G. Mirmira, Bobbie‐Jo M. Webb‐Robertson, Thomas O. Metz, Emily K. Sims, Ernesto S. Nakayasu   +9 more
wiley   +1 more source

[Family and extrafamily dynamics in older adults with low pharmacological treatment adherence in a heart failure program in Santander, Colombia]. [PDF]

Aten Primaria
Torres Montenegro CC, Torres Pinzón H, Therán León JS, Echeverría Correa LE.   +3 more
europepmc   +1 more source

Management and incipient domestication of Chamaedorea tepejilote in agroforestry systems in Mexico

PLANTS, PEOPLE, PLANET, EarlyView.
Native wild plants are key elements in addressing global biodiversity loss and supporting sustainable food systems. We investigated how rural communities in Mexico manage Chamaedorea tepejilote, a wild palm with edible male inflorescences, by combining ethnobotanical, genetic, morphological and ecological approaches.
Viviana Andrade, Alejandro Casas, Edna Arévalo‐Marín, Gonzalo D. Álvarez‐Ríos, Hernán Alvarado‐Sizzo, Vanessa Guerrero‐Hernández, Paola Ubiergo‐Corvalán, Maite Lascurain‐Rangel   +7 more
wiley   +1 more source

[Glycemic control of type 2 diabetes: primary care pre-pandemic versus COVID-19 pandemic]. [PDF]

Rev Med Inst Mex Seguro Soc
Soto-Estrada G, Mares-Gutiérrez Y, García-Minjares M, Martínez-González A, Martínez-Franco AI.   +4 more
europepmc   +1 more source

A Simple Cell Culture Assay for Human Prostatic Branching Morphogenesis Spotlights Bone Morphogenetic Protein Signaling as a Therapeutic Target in Benign Prostatic Hyperplasia

The Prostate, EarlyView.
ABSTRACT Background Benign prostatic hyperplasia (BPH) leads to prostate enlargement and lower urinary tract symptoms that can resist treatment. A histologic hallmark of BPH is glandular epithelial hyperplasia with new ductal branching morphogenesis. The stromal inductive factors driving tissue morphogenesis may provide new therapeutic targets, but are
Anna S. Pollack, James D. Brooks, Jonathan R. Pollack   +2 more
wiley   +1 more source

Gestational syphilis and prenatal care: a study in light of individual, social, and programmatic vulnerabilities. [PDF]

Rev Esc Enferm USP
Sarefino AO, Queiroz ABA, Silva KG, Souza NVDO, Titara NML, Carvalho ALO, Bezerra JDF, Pinheiro AKC, Rosa AFD.   +8 more
europepmc   +1 more source

Programming Multidomain Peptides With Molecular Frustration Into Biomolecular Condensates

Small, EarlyView.
De novo designed multidomain peptides (MDPs) were used to explore how molecular ordering influences peptide phase behavior. MDPs containing partially folded β‐sheets were found to form biomolecular condensates. This work introduces a new design principle for condensate formation and expand the design space beyond conventional intrinsically disordered ...
Debdatta Das, Jenny N. Nguyen, Navneet Sahoo, Chuanye Xiong, Haritha Asokan‐Sheeja, Yan Chang, Raniyah Ali, Eleanor D. Smith, Chad A. Brautigam, Yi Hong, Zui Pan, Peng Tao, He Dong   +12 more
wiley   +1 more source

Reverse‐Engineered Lipid Nanoparticles Harness Protein Corona Formation for Cytokine Sequestration and Combination Immunomodulatory Therapy

Small, EarlyView.
Bioinspired triglyceride‐ceramide lipid nanoparticles were reverse‐engineered from cytokine‐sequestering plant‐derived nanoparticles to capture pathological inflammatory mediators through protein corona formation. Dexamethasone‐loaded TCNPs combine extracellular cytokine sequestration with intracellular immunomodulation, reducing IL‐6, TNF‐α, and NF‐κΒ
Junsik J. Sung, Gargi Yogesh Digholkar, Ryan M. Pearson   +2 more
wiley   +1 more source

Health literacy and its sociodemographic and health determinants. [PDF]

Rev Esc Enferm USP
Ribas C, Colet CF, Morelos-Garcia EN, Valentim OMMS, Strassburger Junior M, Camera FDM, Rusch CR, Kolankiewicz ACB.   +7 more
europepmc   +1 more source

Cyanopeptide Mixtures Induce Variable Synergistic and Antagonistic Effects Across Diverse Human Cell Lines

Environmental Toxicology, EarlyView.
ABSTRACT Cyanobacterial harmful algal blooms (cyanoHABs) threaten human, animal, and ecosystem health and safety through production of toxic secondary metabolites. Microcystis, a cosmopolitan bloom‐forming cyanobacterial genus, is well‐known for producing hepatotoxic microcystins (MCs), but it can produce many other bioactive cyanopeptides, such as ...
Lauren N. Hart, Katherine L. Lev, Sierra Hefferan, Sanduni H. Premathilaka, Sharmila I. Thenuwara, Dragan Isailovic, David H. Sherman, Gregory J. Dick   +7 more
wiley   +1 more source