Results 171 to 180 of about 61,830,977 (255)

Recent Advances (2023–2025) of Capillary Electrophoresis‐Mass Spectrometry (CE‐MS) for Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Top‐down proteomics (TDP) characterizes proteoforms in cells, tissues, and biofluids, in discovery mode and on a global scale, requiring analytical tools with high peak capacity for proteoform separation and high sensitivity for proteoform detection, given the extremely high proteoform complexity and wide proteoform concentration dynamic range.
Guijie Zhu, David A. Alvarez Rodriguez, Noah Gould, Alexander R. Ivanov, Kevin Jooß, Liangliang Sun   +5 more
wiley   +1 more source

Tuberculosis in the South America's homeless: a systematic review of social determinants, control strategies and health equity. [PDF]

Rev Esc Enferm USP
Ramos EM, Sisti CB, Lima SBA, Araújo ELL, Guerra LDDS, Polubriaginof C, Guimarães AMS.   +6 more
europepmc   +1 more source

Redefining CHI3L1: Therapeutic Opportunities at the Crossroads of Immune Suppression and Disease Progression

Medicinal Research Reviews, EarlyView.
ABSTRACT Chitinase‐3‐like‐1 (CHI3L1, also known as YKL‐40) has been recognized as a biomarker of inflammation and tissue remodeling and has now emerged as a pseudoenzymatic immune checkpoint. Recent structural, immunological, and translational studies redefine it as an active regulator of immune suppression rather than a passive disease marker. Despite
Kirti Upmanyu, Saurabh Upadhyay, Moustafa T. Gabr   +2 more
wiley   +1 more source

[Health disparities and legislative determinants in Latin America: Multivariate comparative analysis of life expectancy, infant mortality, and immunization in Chile, Colombia, and Honduras (2011-2019)]. [PDF]

Aten Primaria
Estupiñan Ruiz CA, Correa-Arrieta C, Hincapié-Carvajal JA.   +2 more
europepmc   +1 more source

Molecular Glue Degraders in Early Development for Cancer Therapy

Medicinal Research Reviews, EarlyView.
ABSTRACT Molecular glue degraders are an emerging class of small molecule allosteric modulators that induce or stabilize protein‐protein interactions, enabling targeted degradation of previously intractable proteins. By redirecting E3 ligases to recognize neosubstrates, proteins that are not typically recognized by a specific E3 ubiquitin ligase, they ...
E. Sila Ozdemir, Hyunbum Jang, Ozlem Keskin, Attila Gursoy, Ruth Nussinov   +4 more
wiley   +1 more source

Global strategy for women's health: use of clinical simulation in gestational risk assessment. [PDF]

Rev Bras Enferm
Oliveira SC, Oriá MOB, Souza KV.
europepmc   +1 more source

1D Pre‐Acquisition Navigator Correcting Respiratory‐Induced Field Fluctuations in Multi‐Echo Gradient‐Echo Imaging of the Thoracic Spinal Cord

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose In the spinal cord (SC), multi‐echo gradient echo (ME‐GRE) increases gray (GM) and white matter (WM) contrast and improves sensitivity to lesions in people with multiple sclerosis (pwMS). However, SC ME‐GRE is susceptible to breathing‐induced field fluctuations, causing ghosting artifacts and signal loss.
Alicia E. Cronin, Alexandre D'Astous, Nathan Williams, Antoine Guénette, Aimee Salakhov, Seth Stubblefield, Colin D. McKnight, Lipika Narisetti, Subramaniam Sriram, Seth A. Smith, Ryan K. Robison, Guillaume Gilbert, Julien Cohen‐Adad, Kristin P. O'Grady   +13 more
wiley   +1 more source

Reflexiones desde la experiencia del Sistema General de Seguridad Social en Salud de Colombia: 1993-2026 [PDF]

Rev Colomb Obstet Ginecol
Gaitán Duarte H, Briceño X, Grillo Ardila CF, Rubio Romero JA.   +3 more
europepmc   +1 more source

The Technology Dependence Index (TDI): Development and Validation in Neonatal and Pediatric Populations

Research in Nursing &Health, EarlyView.
ABSTRACT The survival of infants and children with complex medical conditions continues to increase, underscoring the need to quantify technology dependence more effectively. Existing measures emphasize mortality risk and fail to capture the burden of ongoing technological support.
Ashlee J. Vance, Matthew Peterson, Hayley H. Estrem, Christine A. Fortney, Sharron L. Docherty, Debra H. Brandon   +5 more
wiley   +1 more source

[Impact of the national strategy against obesity and diabetes on the incidence of diabetes in Mexico, 2005-2023]. [PDF]

Cad Saude Publica
Fernandez-Contreras L, Saucedo-Sadi C, Molina-Morejón VM.   +2 more
europepmc   +1 more source