Results 111 to 120 of about 3,845,188 (389)

T cell recognition of nonpolymorphic determinants on H-2 class I molecules. [PDF]

open access: yes, 1988
Recognition of polymorphic determinants on class I or class II MHC Ag is required for T lymphocyte responses. Using cell-size artificial membranes (pseudocytes) bearing H-2 class I Ag it is demonstrated that T cells can, in addition, recognize ...
Goldstein, SA, Mescher, MF
core  

Multiplicative anomaly and zeta factorization

open access: yes, 2004
Some aspects of the multiplicative anomaly of zeta determinants are investigated. A rather simple approach is adopted and, in particular, the question of zeta function factorization, together with its possible relation with the multiplicative anomaly ...
Biane P.   +9 more
core   +2 more sources

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

open access: yesFEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang   +2 more
wiley   +1 more source

Towards TB Elimination in Aotearoa/New Zealand: Key Informant Insights on the Determinants of TB among African Migrants

open access: yesTropical Medicine and Infectious Disease, 2018
Migrants living in low incidence countries, including New Zealand (NZ), are disproportionately affected by tuberculosis (TB). This foreign-born group poses important challenges to achieving the national TB elimination targets. Thus, the aim of this study
Emmanuel Badu   +2 more
doaj   +1 more source

Determinants of menstrual hygiene practices among in-school adolescent girls in Osun State, Nigeria: a comparative descriptive cross-sectional study

open access: yesRwanda Medical Journal, 2022
INTRODUCTION: Adolescence in girls has been recognized as a special period that signifies the transition from girlhood to womanhood. This study was conducted to assess the determinants of menstrual hygiene practices among in-school adolescent girls in ...
T. I. Akinreni, O. B.
doaj   +1 more source

Determinants of Commercial Bank Interest Margins and Profitability: Some International Evidence

open access: yes, 1999
Using bank-level data for 80 countries in the year's 1988-95, this article shows that differences in interest margins and bank profitability reflect a variety of determinants: bank characteristics, macroeconomic conditions, explicit and implicit bank ...
Asli Demirgüç-Kunt, H. Huizinga
semanticscholar   +1 more source

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

First trimester medication use in pregnancy in Cameroon: a multi-hospital survey

open access: yesBMC Pregnancy and Childbirth, 2018
Background There is a paucity of epidemiological data on medication use in pregnancy in Cameroon. Methods Between March and August 2015, 795 pregnant women attending 8 urban and 12 rural hospitals in Cameroon for antenatal (ANC) or other care were ...
Aminkeng Zawuo Leke   +9 more
doaj   +1 more source

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