Results 151 to 160 of about 1,027,177 (297)

Self determination [PDF]

British Dental Journal, 2014
openaire   +2 more sources

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

The longevity landscape: mapping stakeholder priorities for healthy aging among high-income countries. [PDF]

BMC Public Health
Mekniran W, Giger OF, Fleisch E, Kowatsch T, Jovanova M.   +4 more
europepmc   +1 more source

Determinants of the decision-to-delivery interval and the effect on perinatal outcome after emergency caesarean delivery: a cross-sectional study.

, 2021
Omotayo M Ayeni, AP Aboyeji, Munirdeen Ijaiya, Kikelomo T. Adesina, Adegboyega A Fawole, Abiodun S. Adeniran   +5 more
openalex   +2 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Tackling child poverty in the UK. [PDF]

BMJ Paediatr Open
Hayre J.
europepmc   +1 more source

Determinate Mutation [PDF]

Science, 1905
openaire   +2 more sources

Capital Structure Determinants: New Evidence from French Panel Data

, 2011
Mondher Kouki, Hatem Ben Said
openalex   +2 more sources

IL-1β as a determinant in silica-induced cytokine responses in monocyte-endothelial cell co-cultures [PDF]

, 2008
J. I. Herseth, Magne Refsnes, Marit Låg, Geir Hetland, PE Schwarze   +4 more
openalex   +1 more source