Results 91 to 100 of about 397,912 (346)

Psychosocial interventions and opioid detoxification for drug misuse: summary of NICE guidance [PDF]

, 2007
Drug misuse is an increasing problem that not only impairs the physical and mental health of people who misuse drugs but also negatively affects their families and wider society (for example, in its association with crime).
Gerada, Clare, Pilling, Stephen, Strang, John   +2 more
core  

Differential activities of glutathione s-transferase isoenzymes in strains of fasciola hepatica susceptible and resistant to triclabendazole [PDF]

, 2014
Fasciolosis, a parasitic zoonosis of intrahepatic location, is caused by the trematode Fasciola hepatica. Its control is mainly based on the use of the anthelminthic Triclabendazole (TCBZ).
Fernandez, Vanesa, Ortiz Oblitas P., Solana, Hugo Daniel, Solana, María Victoria   +3 more
core   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

THE GERMANIUM EXTRACTION FROM TECHNOGENIC RAW MATERIALS BY MICROBIOLOGICAL METHODS [PDF]

, 2018
The results have practical significance and can be the basis for developing a unified biotechnological method of technogenic waste processing with a purpose of their sterilization and detoxification with simultaneous obtaining ...
Blaida, Iryna, Ivanytsia, Volodymyr, Sliusarenko, Larysa, Vasylieva, Tetiana   +3 more
core  

Receptor‐Free Identification of Toxic Gases Enabled by Hygroscopic Aqueous Salt Films

Advanced Functional Materials, EarlyView.
Water as a gas sensor coating sounds impossible—until it stops evaporating. Here, hygroscopic salt solutions (LiCl, LiBr, H3PO4) form non‐drying aqueous films on CNT chemiresistors under ambient air. Gases partition into these liquid layers, sometimes transforming into water, and generate salt‐specific resistance fingerprints across a four‐channel ...
Seongwoo Lee, Yun‐Tae Kim, Hwarang Choi, Sanghwan Park, Seongyeop Lim, Chang Young Lee   +5 more
wiley   +1 more source

Live to cheat another day: bacterial dormancy facilitates the social exploitation of beta-lactamases [PDF]

, 2015
The breakdown of antibiotics by β-lactamases may be cooperative, since resistant cells can detoxify their environment and facilitate the growth of susceptible neighbours. However, previous studies of this phenomenon have used artificial bacterial vectors
A Bloor, A Brooun, A Ross-Gillespie, A Ross-Gillespie, AS Hackman, B Raymond, B Raymond, Ben Raymond, BR Levin, C Dahlberg, D Clark, DA Mitchison, DM Livermore, E Tuomanen, EA Yurtsev, Frances Medaney, G Rolinson, GL Hobby, HC Neu, I Brook, I Brook, JJ Harrison, JL Cottell, JW Bigger, K Datsenko, K Lewis, K Lewis, K Lewis, K Sandoz, L Dugatkin, L Zhou, M Doebeli, M Ghoul, MH Perlin, NQ Balaban, O Ciofu, PS Stewart, R Ellis, R Lenski, R Lenski, R Tacking, Richard J Ellis, RJ Worthington, RM Cozens, RN Jones, S Brown, SA West, SA West, SP Brown, SP Diggle, Tatiana Dimitriu, X-X Zhang, XX Zhang   +52 more
core   +1 more source

Nanodiamond Quantum Sensors for Probing Free Radical Biology

Advanced Functional Materials, EarlyView.
Free radicals play key roles in cellular signaling and disease but remain difficult to measure in living systems. Nanodiamonds (NDs) with nitrogen‐vacancy (NV) centers enable quantum sensing of local magnetic noise via T₁ relaxometry, providing nondestructive radical detection in living cells.
Qi Lu, Yingke Wu, Tanja Weil
wiley   +1 more source

Cross-education Mechanisms and Clinical Rehabilitation Research: A Literature Review

Quality in Sport
In recent years, cross-education has garnered significant attention in the fields of clinical rehabilitation and sports training. Since the discovery of CE, a growing number of studies have focused on understanding its characteristics for deeper insight
Liang Sun, Yi Wang, Lanfang Luo, Yi Yang, Jiong Luo   +4 more
doaj   +1 more source

The phytopathogenic fungus Sclerotinia sclerotiorum detoxifies plant glucosinolate hydrolysis products via an isothiocyanate hydrolase

Nature Communications, 2020
Some plants produce toxic isothiocyanates that protect them against pathogens. Here, Chen et al. show that the plant pathogenic fungus Sclerotinia sclerotiorum converts isothiocyanates into non-toxic compounds via glutathione conjugation and, more ...
Jingyuan Chen, Chhana Ullah, Michael Reichelt, Franziska Beran, Zhi-Ling Yang, Jonathan Gershenzon, Almuth Hammerbacher, Daniel G. Vassão   +7 more
doaj   +1 more source

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source