Results 111 to 120 of about 279,100 (350)

Bioprocessing of Functional Ingredients from Flaxseed

Molecules, 2018
Flaxseeds (Linum usitatissimum L.) are oilseeds endowed with nutritional constituents such as lignans, lipids, proteins, fibre, carbohydrates, and micronutrients.
Christian Kwesi Ofotsu Dzuvor, Jordan Tauai Taylor, Caleb Acquah, Sharadwata Pan, Dominic Agyei   +4 more
doaj   +1 more source

Mechanism of malarial haem detoxification inhibition by chloroquine

, 2001
The haem detoxification pathway of the malaria parasite Plasmodium falciparum is a potential biochemical target for drug development. Free haem, released after haemoglobin degradation, is polymerized by the parasite to form haemozoin pigment.
Pandey, Kailash C., Babbarwal, Vinod K., Pandey, Amit V., Bisht, Himani, Srivastava, Jaya, Chauhan, Virander S., Pandey, Amit Vikram   +6 more
core   +1 more source

HNRNPU K181 Lactylation Drives Cervical Cancer Growth by Upregulating PHGDH and Reprogramming Serine Metabolism

Advanced Science, EarlyView.
Lactate in cervical cancer induces HNRNPU K181 lactylation, opposed by NAA50‐mediated acetylation and suppressed by Pazopanib. This lactylation enhances HNRNPU binding to PHGDH pre‐mRNA exon 1, maintaining exon 1‐containing transcripts and mRNA stability, thereby activating serine metabolism.
Chang Zhang, Qingfei Meng, Hui Jiao, Huixin Liu, Xiangchao Wang, Honglan Zhou, Yishu Wang   +6 more
wiley   +1 more source

Exploring the relationship between cue-induced craving and withdrawal craving in MUD individuals based on a virtual-reality cue exposure paradigm

BMC Psychiatry
Background This study developed a virtual reality (VR) drug cue exposure paradigm for individuals with methamphetamine use disorder (MUD) to investigate the characteristics of withdrawal craving and cue-induced craving and their relationship.
Qiuping Huang, Xinxin Chen, Ying Tang, Xuhao Wang, Wenwu Wang, Li Chao, Yiqi Nie, Shihua Peng, Lin Zhao, Hongxian Shen, Zhenjiang Liao   +10 more
doaj   +1 more source

A Greater Capacity of Metallothionein Synthesis: Would it be Sufficient as Explanation for the Absence of Pathological Effects in Marine Mammals with Extremely High Cd Concentrations? A Review

Orbital: The Electronic Journal of Chemistry, 2018
Several studies have shown that marine mammals, especially the oceanic ones, present extremely high Cd concentrations. As the phenomenon of Cd transfer from cephalopods to cetaceans seems to be natural, the most plausible reason for the perpetuation of ...
Paulo Renato Dorneles, André Pinheiro de Almeida, Olaf Malm   +2 more
doaj   +1 more source

Detoxification of Rapeseed Products

Journal of Food Protection, 1981
The full potential of rapeseed products has not yet been realized because of the presence of certain toxic compounds. This paper reviews development of low erucic acid rapeseed, and the extensive experimental scrutiny to which this oil has been subjected.
P N, Maheshwari, D W, Stanley, J I, Gray
openaire   +2 more sources

Integration of Spatiotemporal Multi‐Omics in Peach Fruit Unravels a Metabolic Niche and the Genetic Basis of Trichome‐Mediated Stress Adaptation

Advanced Science, EarlyView.
This study constructed the first spatiotemporal multi‐omics map of peach fruit and discovered a key candidate gene that synergistically regulates trichome development and drought tolerance through the jasmonic acid signaling pathway, providing insights into the coupling mechanism between development and stress resistance.
Zhixin Liu, Ke Cao, Liping Guan, Aizhi Qin, Yong Li, Zihao Zhao, Yinpeng Zhang, Yaping Zhou, Lirong Wang, Xuwu Sun   +9 more
wiley   +1 more source

Disruption of Treg Homeostasis in Rheumatoid Arthritis via Ferroptosis‐Mediated ETC Collapse and TXK‐STAT3/PLCγ1 Activation

Advanced Science, EarlyView.
In rheumatoid arthritis, synovial Tregs accumulate but are functionally impaired due to iron overload‐induced ferroptosis. This triggers mitochondrial dysfunction and TXK tyrosine kinase‐mediated signaling, leading to Treg destabilization and inflammation.
Jingrong Chen, Xiao Guan, Kexu Xiong, Xiaoyi Shi, Luyao Wu, Chuanxin Su, Jun Zhao, Rongzhen Liang, Huimin Wang, Junlong Dang, Ye Chen, Yiding Xiong, Chi Zhou, Futao Zhao, Zhenhang Zhu, Xiaoli Fan, Li Zhou, Nancy Olsen, Yutong Jiang, Song Guo Zheng   +19 more
wiley   +1 more source

A review of a 7-day alcohol detoxification compared with a 5-day detoxification program

, 2021
Purpose of Project: The objective of this project aimed at standardizing the length of stay (LOS) for alcohol detoxification admission by showing that a 7-day stay as compared to a 5-day stay resulted in decreased CIWA scores and lower Librium doses ...

core   +1 more source

Two Routes to Land: Genomic Underpinnings of Parallel Aerial Egg Deposition in Aquatic Old‐World Pila and New‐World Pomacea (Ampullariidae)

Advanced Science, EarlyView.
Comparative genomics of Gondwana‐diverged Pila and Pomacea reveals parallel evolution of aerial oviposition. Convergent chromosomal rearrangements reshape regulatory landscapes within topologically associating domains. Lineage‐specific gene family expansions and viral‐derived perivitelline proteins (PV1) underpin desiccation resistance.
Yufei Zhou, Huawei Mu, Xueying Nie, Yue Gao, Hui Wang, Ling Fang, Tiangang Luan, Monthon Ganmanee, Jian‐Wen Qiu, Jin Sun, Jack Chi‐Ho Ip   +10 more
wiley   +1 more source