Results 51 to 60 of about 159,676 (255)

HNRNPU K181 Lactylation Drives Cervical Cancer Growth by Upregulating PHGDH and Reprogramming Serine Metabolism

Advanced Science, EarlyView.
Lactate in cervical cancer induces HNRNPU K181 lactylation, opposed by NAA50‐mediated acetylation and suppressed by Pazopanib. This lactylation enhances HNRNPU binding to PHGDH pre‐mRNA exon 1, maintaining exon 1‐containing transcripts and mRNA stability, thereby activating serine metabolism.
Chang Zhang, Qingfei Meng, Hui Jiao, Huixin Liu, Xiangchao Wang, Honglan Zhou, Yishu Wang   +6 more
wiley   +1 more source

Transformações Metabólicas de Agrotóxicos em Peixes: Uma Revisão

Orbital: The Electronic Journal of Chemistry, 2016
Fish are among the organisms most damaged by aquatic contamination by pesticides, being ecologically relevant for their bioaccumulation and biomagnification skills of contaminants, which may present health risks to fish consumers.
Ligia Maria Borges Marques Santana, Rivelino Martins Cavalcante   +1 more
doaj   +3 more sources

Relationship between state anxiety, heart rate variability, and shooting performance in adolescent shooters

BMC Psychology
Objective By comparing the differences in pre-competition state anxiety, inter-competition heart rate variability (HRV), and shooting performance of young athletes of different grades, and revealing the correlation between these variables, it provides a ...
Chaochao Zhao, Kun Wang, Dan Li, Yan Li, Zhuo Wang, Yongsen Liu, Tingran Zhang   +6 more
doaj   +1 more source

COGNITIVE DYSFUNCTIONS IN PATIENTS OF MIDDLE, ELDERLY AND OLD AGE IN THE LONG-TERM PERIOD AFTER CHOLECYSTECTOMY

Паёми Сино, 2019
Objective: To study the state of cognitive dysfunction in patients of middle, elderly and old age in the long-term period after cholecystectomy Methods: A study conducted on the state of cognitive dysfunctions in 306 patients with cholelithiasis ...
M.K. GULOV, A.M. SAFARZODA
doaj   +1 more source

Two Routes to Land: Genomic Underpinnings of Parallel Aerial Egg Deposition in Aquatic Old‐World Pila and New‐World Pomacea (Ampullariidae)

Advanced Science, EarlyView.
Comparative genomics of Gondwana‐diverged Pila and Pomacea reveals parallel evolution of aerial oviposition. Convergent chromosomal rearrangements reshape regulatory landscapes within topologically associating domains. Lineage‐specific gene family expansions and viral‐derived perivitelline proteins (PV1) underpin desiccation resistance.
Yufei Zhou, Huawei Mu, Xueying Nie, Yue Gao, Hui Wang, Ling Fang, Tiangang Luan, Monthon Ganmanee, Jian‐Wen Qiu, Jin Sun, Jack Chi‐Ho Ip   +10 more
wiley   +1 more source

Original Article. Effect of cold plasma on degradation of organophosphorus pesticides used on some agricultural products

Journal of Plant Protection Research, 2016
This study investigated the potential effect of cold plasma on reducing residues of pesticides diazinon and chlorpyrifos in apples and cucumbers and its effects on property of products. Two separate concentrations of each pesticide with 500 and 1,000 ppm
Mousavi Seyyedeh Mahbubeh, Imani Sohrab, Dorranian Davoud, Larijani Kambiz, Shojaee Mahmoud   +4 more
doaj   +1 more source

BIN1 and ALDH1B1 Deficiency in Colonic Smooth Muscle Drives Mitochondrial Dysfunction and Fibrosis in Slow‐Transit Constipation

Advanced Science, EarlyView.
Slow‐transit constipation (STC) is a disabling motility disorder with unclear smooth‐muscle mechanisms. Spatial proteomic analysis of STC patient colon reveals both the central pathogenic role of smooth muscle cells (SMCs) in STC and novel regulators of intestinal motility, BIN1 and ALDH1B1.
Jianbo Liu, Hao Zhang, Wenhao Qiao, Ran Liu, Jie Sun, Xiaopei Li, Qin Li, Dongbo Zhao, Dawei Chen, Jingxin Li, Shuxiao Dong   +10 more
wiley   +1 more source

Streptavidins Coordinate Biotin Sequestration and Self‐Resistance Within a Biotin‐Pathway Antibiotic Network

Advanced Science, EarlyView.
A conserved genomic region between two streptavidin genes in Streptomyces packages biosynthetic gene clusters for diverse biotin‐pathway antibiotics: acidomycin, stravidin, the new non‐proteinogenic amino acid ANDA, and the new BioA inhibitor α‐methyl‐KAPA.
Sumire Kurosawa, Jingjun Mo, Xiaotong Diao, Feng Xie, Tingting Wang, Haowen Zhao, Dalei Wu, Rolf Müller, Chengzhang Fu   +8 more
wiley   +1 more source

Zinc detoxification by a cyanobacterium from a metal contaminated bay in Brazil

Brazilian Archives of Biology and Technology, 2004
We describe here the trapping of zinc in polyphosphate granules of the cyanobacterium Synechocystis aquatilis NPBS-3. Cells were cultured in 25 µM of zinc chloride and prepared for electron microscopy and energy-dispersive X-ray analysis.
Luciana Andrade, Carolina N. Keim, Marcos Farina, Wolfgang C. Pfeiffer   +3 more
doaj   +1 more source

Optimized Ex Vivo Human Liver Slice Culture Maintains Extended Viability and Function for Hepatotoxicity Testing

Advanced Science, EarlyView.
An optimized ex vivo human liver slice culture system preserves tissue architecture, hepatocyte function, and immune‐stromal complexity for at least five days. By refining slice thickness, oxygenation, air‐liquid interface, and extracellular matrix support, the platform enables human‐relevant hepatotoxicity testing and mechanistic studies, offering a ...
Huiche Feng, Cinzia Esposito, Andrej Benjak, Matthias S. Matter, Miriam Cieri, Camilla De Carlo, Philipp Sedlaczek, Fabian Haak, Mattia Marinucci, Gabriel Fridolin Hess, Otto Kollmar, Mairene Coto‐Llerena, Luca Di Tommaso, Visar Vela, Lukas Bubendorf, Luigi M. Terracciano, Charlotte K. Y. Ng, Salvatore Piscuoglio   +17 more
wiley   +1 more source