Selective review and commentary on emerging pharmacotherapies for opioid addiction. [PDF]
, 2011 Pharmacotherapies for opioid addiction under active development in the US include lofexidine (primarily for managing withdrawal symptoms) and Probuphine®, a distinctive mode of delivering buprenorphine for six months, thus relieving patients, clinicians,
Ling, Walter +5 more
core +2 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
BMC PsychologyObjective To investigate the relationship between internet use, physical activity, social adaptability, and depressive tendencies of college students, and to reveal the “advantages” and “disadvantages” of internet use around the “dose-effect”. Method The
Kun Wang +4 more
doaj +1 more source
Quality in SportObjective: This review aims to understand the mental health status of college students during the popularity of covid-19, and explore the impact of sports intervention on College Students' mental health and its path mechanism through a literature review.
Yi Yang +4 more
doaj +1 more source
Human colonocyte detoxification [PDF]
Gut, 1997 Detoxification or biotransformation of drugs and xenobiotics are usually linked with liver metabolism, yet colonocytes of the gastrointestinal tract have an equal capacity to mediate these processes.1 2 This brief overview specifically discusses the ability of human colonocytes, but not other tissues, to detoxify chemical agents and relates pertinent ...
Roediger, W., Babidge, W.
openaire +3 more sources
Factors associated with discharge against medical advice from an inpatient alcohol and drug detoxification unit in Barcelona during 1993-2006 [PDF]
, 2012 Records from 1,228 consecutively admitted patients (74.5% male) to an inpatient detoxification unit in Barcelona during 1993-2006 were examined to determine factors associated with discharge against medical advice (AMA).
Fonseca, Francina +4 more
core
Bistable equilibrium points of mercury body burden [PDF]
, 2007 In the last century mercury levels in the global environment have tripled as a result of increased pollution from industrial, occupational, medicinal and domestic uses \cite{BaMe03}. Glutathione is known to be the main agent responsible for the excretion
Boulos, Areen, Owhadi, Houman
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In vitro rumen simulations show a reduced disappearance of deoxynivalenol, nivalenol and enniatin B at conditions of rumen acidosis and lower microbial activity [PDF]
, 2020 Ruminants are generally considered to be less susceptible to the effects of mycotoxins than monogastric animals as the rumen microbiota are capable of detoxifying some of these toxins.
Cools, An +6 more
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Integrated stress response of Escherichia coli to methylglyoxal : transcriptional readthrough from the nemRA operon enhances protection through increased expression of glyoxalase I [PDF]
, 2013 © 2013 The Authors.
Booth, Ian R +4 more
core +1 more source