Results 211 to 220 of about 27,539 (236)

Role of Ubiquitin-regulated EMT in Cancer Metastasis and Chemoresistance. [PDF]

Int J Biol Sci
Xiao S, Tian L, Gan X, Xu X, Liao M, Song D, Yu Y, Qin W, Zhang R, Lyu H, Guo D, Zhang Q, Chen XZ, Zhou C, Tang J.   +14 more
europepmc   +1 more source

Obestatin Treatment Counteracts Muscle Wasting by Reactivation of Autophagy in Duchenne Muscular Dystrophy. [PDF]

MedComm (2020)
Santos-Zas I, Costas-Abalde S, Lodeiro AC, Fernández-Barreiro F, Cid-Díaz T, Leal-López S, González-Sánchez J, García-Lamela M, Debasa-Corral L, Mosteiro CS, Mamchaoui K, Mouly V, Casabiell X, Gallego R, Relova JL, Pazos Y, Camiña JP.   +16 more
europepmc   +1 more source

YKT6 Promotes Bladder Cancer Progression by Stabilizing β-catenin Through USP7-Mediated Deubiquitination. [PDF]

Adv Sci (Weinh)
Tu S, Du W, Luo Y, Shi J, Liu T, Ji M, Xiong K, Chen S, Zhou F, Li M, Yu J, Wang G, Ju L, Zhang Y, Xiao Y, Wang X, Qian K.   +16 more
europepmc   +1 more source

PSMD14 drives lung adenocarcinoma progression through HMMR stabilization and dual activation of TGF-β/Smad and PI3K/AKT/mTOR signaling. [PDF]

Front Immunol
Chen R, Wang S, Xie J.
europepmc   +1 more source

Deubiquitinating Enzymes in Osteoarthritis: From Mechanisms to Therapeutic. [PDF]

Orthop Rev (Pavia)
Yuan Z, Chen G, Li Y, Zhao Z, Zhang H.
europepmc   +1 more source

From concept to application: Exploring the evolution and potential of DUBTAC technology. [PDF]

Acta Pharm Sin B
Wang D, Min W, Jiang B, Sun H, Sun C, Yang P.   +5 more
europepmc   +1 more source

USP7 sustains hematopoietic stem cell homeostasis partially via PU.1 stabilization. [PDF]

Int J Biol Sci
Shan H, Zhang Y, Xiao X, Wu W, Wang Y, Zhu C, Bai W, Zhang Z, Zhai Y, Yang L, Wu Y, Lei H, Xu H, Luo Y, Lu L, Wu Y.   +15 more
europepmc   +1 more source

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Deubiquitinating enzyme YOD1 deubiquitinates and destabilizes α-synuclein

Biochemical and Biophysical Research Communications, 2023
α-synuclein is one of the proteins involved in degenerative neuronal diseases such as Parkinson's disease (PD) or Lewy body dementia (LBD). The pathogenesis is imparted by the abnormal accumulation of α-synuclein resulting in the formation of a Lewy body (LB) and exerting neurotoxicity via an unknown mechanism.
Sang-Soo Park, Hyeon-Ah Do, Hong-Beom Park, Hae-Seul Choi, Kwang-Hyun Baek   +4 more
openaire   +2 more sources

USP7 Deubiquitinates and Stabilizes SIRT1

The Anatomical Record, 2019
ABSTRACTThe NAD+‐dependent protein deacetylase silent information regulator 1 (SIRT1) targets multiple proteins for deacetylation, and it has been implicated in a variety of cellular pathways and human diseases. However, it remains unclear how the abundance of SIRT1 is regulated. Here, by mass spectrometry analysis of SIRT1‐containing protein complexes,
Nan Song, Cheng Cao, Shanshan Tian, Meijing Long, Ling Liu   +4 more
openaire   +2 more sources