Results 221 to 230 of about 28,234 (247)

Targeting Deubiquitinating Enzymes

2009
Deubiquitinating enzymes (DUBs) or isopeptidases belong to the enzyme class of hydrolases which include more than 100 members identified thus far. These proteins, which are grouped into four cysteine protease families and one metallo-protease family, catalyze the removal of ubiquitin from specific protein targets by cleavage of the linking isopeptide ...
Carmen Priolo, Derek Oldridge, Martin Renatus, Massimo Loda   +3 more
openaire   +1 more source

Identification of a Deubiquitinating Enzyme

Science, 2007
Modification of proteins by the covalent attachment of ubiquitin chains has emerged as a major regulatory mechanism in cells. The enzymes that oppose this reaction, the deubiquitinating enzymes, are relatively poorly understood. Kayagaki et al.
openaire   +2 more sources

The role of ubiquitination and deubiquitination in PI3K/AKT/mTOR pathway: A potential target for cancer therapy

Gene, 2023
Xiaofeng Jin
exaly  

Regulation of Hedgehog Signal Transduction by Ubiquitination and Deubiquitination

International Journal of Molecular Sciences, 2021
Jin Jiang
exaly  

Deubiquitination

2020
openaire   +1 more source

The potential role of ubiquitination and deubiquitination in melanogenesis

Experimental Dermatology, 2023
Shuaishuai Hu, Lu Wang, Shuaishuai Hu
exaly  

Carrier-free quercetin nanomedicine blocks NLRP3 deubiquitination and TXNIP recruitment for Parkinson’s disease therapy

Chemical Engineering Journal, 2023
Yan Dou
exaly  

214: The deubiquitinating enzyme USP15 deubiquitinates the E3 ligase SMURF2

European Journal of Cancer, 2014
P. Iyengar, P. Jaynes, P. Eichhorn
openaire   +1 more source

microRNA-362-3p targets USP22 to retard retinoblastoma growth via reducing deubiquitination of LSD1

Cell Cycle, 2021
Zhigang Li, Guangying Zheng
exaly  

Dual roles of the Arabidopsis PEAT complex in histone H2A deubiquitination and H4K5 acetylation

Molecular Plant, 2023
exaly