Results 11 to 20 of about 273,322 (239)

Deuterium Labeling of Isoaspartic and Isoglutamic Acids for Mass Spectrometry Analysis. [PDF]

Anal Chem
Isoaspartic acid (isoAsp) is a common protein modification that spontaneously arises from asparagine or aspartic acid, and it has been linked to various diseases and health conditions.
Miyagi M, Kiesel E, Neumbo K, Nakazawa T.   +3 more
europepmc   +6 more sources

Defective Ultrathin ZnIn2S4 for Photoreductive Deuteration of Carbonyls Using D2O as the Deuterium Source

Advanced Science, 2022
Deuterium (D) labeling is of great value in organic synthesis, pharmaceutical industry, and materials science. However, the state‐of‐the‐art deuteration methods generally require noble metal catalysts, expensive deuterium sources, or harsh reaction ...
Chuang Han, Guanqun Han, Shukai Yao, Lan Yuan, Xingwu Liu, Zhi Cao, Arun Mannodi‐Kanakkithodi, Yujie Sun   +7 more
doaj   +1 more source

Deuterium Isotope Probing: a potential game-changer in assessing chemical persistency in soil [PDF]

, 2023
Chemical persistency studies are crucial for the regulatory risk assessment of chemicals. One of their major challenges is the formation of so-called non-extractable residues (NERs) in soil as current analytics cannot easily differentiate hazardous ...
Sophie, Lennartz, Martin, Krauss, Harriet A., Byrne, Karolina, Nowak, Steffen, Kümmel, Sophie Lennartz, Martin Krauss, Harriet A. Byrne, Karolina Nowak, Steffen Kümmel   +9 more
core   +1 more source

Deuterium Depletion Inhibits Cell Proliferation, RNA and Nuclear Membrane Turnover to Enhance Survival in Pancreatic Cancer

Cancer Control, 2021
The effects of deuterium-depleted water (DDW) containing deuterium (D) at a concentration of 25 parts per million (ppm), 50 ppm, 105 ppm and the control at 150 ppm were monitored in MIA-PaCa-2 pancreatic cancer cells by the real-time cell impedance ...
László G. Boros, Ildikó Somlyai, Beáta Zs. Kovács, László G. Puskás, Lajos I. Nagy, László Dux, Gyula Farkas, Gábor Somlyai   +7 more
doaj   +1 more source

Rapid detection of antimicrobial resistance in methicillin-resistant Staphylococcus aureus using MALDI-TOF mass spectrometry

Frontiers in Cellular and Infection Microbiology, 2023
Antimicrobial resistance is a growing problem in modern healthcare. Most antimicrobial susceptibility tests (AST) require long culture times which delay diagnosis and effective treatment. Our group has previously reported a proof-of-concept demonstration
Josiah J. Rensner, Paul Lueth, Bryan H. Bellaire, Orhan Sahin, Young Jin Lee   +4 more
doaj   +1 more source

Skeletal Muscle Nuclei in Mice are not Post-mitotic

Function, 2023
The skeletal muscle research field generally accepts that nuclei in skeletal muscle fibers (ie, myonuclei) are post-mitotic and unable to proliferate. Because our deuterium oxide (D2O) labeling studies showed DNA synthesis in skeletal muscle tissue, we ...
Agnieszka K Borowik, Arik Davidyan, Frederick F Peelor, Evelina Voloviceva, Stephen M Doidge, Matthew P Bubak, Christopher B Mobley, John J McCarthy, Esther E Dupont-Versteegden, Benjamin F Miller   +9 more
doaj   +1 more source

Simple Deuterium Introduction at α-Position of Carbonyl in Diazirinyl Derivatives for Photoaffinity Labeling [PDF]

, 2010
Post-functional deuterium incorporation into diazirinyl acetophenone derivatives is reported. Treatment of the compounds with sodium hydroxide in CH3OD at rt for 10 min achieved deuterium incorporation at α-position of the carbonyl group without ...
Yasumaru Hatanaka, Muto, Yasuyuki, Hashimoto, Makoto, Takahashi, Miho, Yasuyuki Muto, Makoto Hashimoto, Murai, Yuta, Hatanaka, Yasumaru, Yuta Murai, Miho Takahashi   +9 more
core   +1 more source

Cell-density independent increased lymphocyte production and loss rates post-autologous HSCT

eLife, 2021
Lymphocyte numbers need to be quite tightly regulated. It is generally assumed that lymphocyte production and lifespan increase homeostatically when lymphocyte numbers are low and, vice versa, return to normal once cell numbers have normalized.
Mariona Baliu-Piqué, Vera van Hoeven, Julia Drylewicz, Lotte E van der Wagen, Anke Janssen, Sigrid A Otto, Menno C van Zelm, Rob J de Boer, Jürgen Kuball, Jose AM Borghans, Kiki Tesselaar   +10 more
doaj   +1 more source

Synthesis of Deuterium-Labeled Vitamin D Metabolites as Internal Standards for LC-MS Analysis

Molecules, 2022
Blood levels of the vitamin D3 (D3) metabolites 25-hydroxyvitamin D3 (25(OH)D3), 24R,25-dihydroxyvitamin D3, and 1α,25-dihydroxyvitamin D3 (1,25(OH)2D3) are recognized indicators for the diagnosis of bone metabolism-related diseases, D3 deficiency ...
Akiko Nagata, Kazuto Iijima, Ryota Sakamoto, Yuka Mizumoto, Miho Iwaki, Masaki Takiwaki, Yoshikuni Kikutani, Seketsu Fukuzawa, Minami Odagi, Masayuki Tera, Kazuo Nagasawa   +10 more
doaj   +1 more source

Small-Angle Neutron Scattering for Studying Lipid Bilayer Membranes

Biomolecules, 2022
Small-angle neutron scattering (SANS) is a powerful tool for studying biological membranes and model lipid bilayer membranes. The length scales probed by SANS, being from 1 nm to over 100 nm, are well-matched to the relevant length scales of the bilayer,
William T. Heller
doaj   +1 more source