Deuterium Oxide Labeling for Global Omics Relative Quantification: Application to Lipidomics
A novel quantitative mass spectrometric method based on partial metabolic deuterium oxide (D2O) labeling, named “Deuterium Oxide Labeling for Global Omics Relative Quantification (DOLGOReQ)”, was developed for relative quantification of lipids on a ...
Jonghyun Kim (693561) +3 more
core +2 more sources
Structure determination of the nonlinear hydrocarbon chains C9H3 and C11H3 by deuterium labeling [PDF]
A systematic deuterium labeling experiment is presented that aims at an unambiguous determination of the geometrical ground state structure of the
Zhao, D. +6 more
core +1 more source
Gold-catalyzed cyclization of allenyl acetal derivatives
The gold-catalyzed transformation of allenyl acetals into 5-alkylidenecyclopent-2-en-1-ones is described. The outcome of our deuterium labeling experiments supports a 1,4-hydride shift of the resulting allyl cationic intermediates because a complete ...
Dhananjayan Vasu +2 more
doaj +1 more source
Memory T-cells are essential to maintain long-term immunological memory. It is widely thought that the bone marrow (BM) plays an important role in the long-term maintenance of memory T-cells.
Mariona Baliu-Piqué +9 more
doaj +1 more source
Vertex Graceful Labeling-Some Path Related Graphs [PDF]
Treating subjects as vertex graceful graphs, vertex graceful labeling, caterpillar, actinia graphs, Smarandachely vertex m ...
Balaganesan, P. +2 more
core +1 more source
Rapid deuterium labeling and localization for structural elucidation of carbohydrates. [PDF]
Carbohydrates are crucial components of life, serving a variety of cellular functions with broad implications. Characterization of carbohydrate structures is a significant step for understanding cell biology.
Kim, H. Jamie, 1992-
core +1 more source
Deuterium-Free, Three-Plexed Peptide Diethylation for Highly Accurate Quantitative Proteomics
The deuterium, a frequently used stable isotope in isotopic labeling for quantitative proteomics, could deteriorate the accuracy and precision of proteome quantification owing to the retention time shift of deuterated peptides from the hydrogenated ...
Hyunjoon Kim (268724) +29 more
core +1 more source
Controllable deuteration of halogenated compounds by photocatalytic D2O splitting
Developing convenient deuterium labeling procedures is important in organic synthesis and the pharmaceutical industry. Here, the authors report a mild photocatalytic strategy for controllable deuteration of halides using D2O as the reagent and porous ...
Cuibo Liu +15 more
doaj +1 more source
Electrochemical selective deuterium labelling of N-heteroarenes
Hydrogen-deuterium exchange (HIE) reaction is the most direct way to achieve the deuterium labeling as there is no need for extra pre-functionalization. Herein, we report an electrochemical selective deuterium labelling of N-heteroarenes using D2O.
Feiyu Qiu +7 more
doaj +1 more source
Raney Nickel-Catalyzed Deuterium Labeling of Nitrogen-Containing Heterocycles and Pharmaceuticals under Continuous Flow Conditions [PDF]
Deuterium-labeled compounds play a pivotal role in physical organic chemistry, life sciences, and materials science. This has resulted in a surge of interest in deuterium-labeled active pharmaceutical ingredients in recent years.
Gellért, Sipos +5 more
core +2 more sources

