Results 31 to 40 of about 77,025 (217)

Tauchfahrt zu einem Methusalem der Meere [PDF]

, 2006
Der Quastenflosser existierte bereits vor 400 Millionen Jahren.
Fricke, Hans, Hissmann, Karen
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Eiskristallen in Wolken auf der Spur : neue DFG-Forschergruppe INUIT nimmt Arbeit auf [PDF]

, 2012
Wie bildet sich Eis in der Atmosphäre? Dieser für die Klimaforschung relevanten Frage geht die neue Forschergruppe »INUIT« nach.

core  

Communication about education and educational science - general pedagogy on an international level. On the contributions by Paul Smeyers, Marc Depaepe et al [PDF]

, 2015
Es ist ja nicht alltäglich, dass eine Gruppe von Forschern, meist außerdeutscher Provenienz, die sich mit Theorie und Geschichte der Erziehung und der Erziehungswissenschaft (in westlichen Kulturen) beschäftigt, nach 15 Jahren gemeinsamer Kommunikation ...
Tenorth, Heinz-Elmar
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Insights into IGH clonal evolution in BCP-ALL: frequency, mechanisms, associations, and diagnostic implications

Frontiers in Immunology, 2023
IntroductionThe malignant transformation leading to a maturation arrest in B-cell precursor acute lymphoblastic leukemia (BCP-ALL) occurs early in B-cell development, in a pro-B or pre-B cell, when somatic recombination of variable (V), diversity (D ...
Franziska Darzentas, Monika Szczepanowski, Michaela Kotrová, Alina Hartmann, Alina Hartmann, Alina Hartmann, Thomas Beder, Thomas Beder, Nicola Gökbuget, Stefan Schwartz, Stefan Schwartz, Lorenz Bastian, Lorenz Bastian, Lorenz Bastian, Claudia Dorothea Baldus, Claudia Dorothea Baldus, Claudia Dorothea Baldus, Karol Pál, Nikos Darzentas, Monika Brüggemann, Monika Brüggemann, Monika Brüggemann   +21 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

TTC: A Tensor Transposition Compiler for Multiple Architectures

, 2016
We consider the problem of transposing tensors of arbitrary dimension and describe TTC, an open source domain-specific parallel compiler. TTC generates optimized parallel C++/CUDA C code that achieves a significant fraction of the system's peak memory ...
Abadi M., Knijnenburg P. M., Knijnenburg P. M., Knijnenburg P. M., Knijnenburg P. M., Knijnenburg P. M., Knijnenburg P. M., Springer P.   +7 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source