Results 41 to 50 of about 77,025 (217)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

"The German language and literature special collections at the University library of Frankfurt am Main and the work of the subject specialist" : paper delivered in Göttingen, 4. 9. 2007, at the annual conference of the German Studies Library Group (GSLG) [PDF]

open access: yes, 2007
Contents - BIX: pole position and runner-up - Frankfurt University Library: its responsibilities, its collections, its databases, its supra-regional collecting responsibilities – and some statistics - The "Sondersammelgebiet" Germanistik: its scope and ...
Giesen, Winfried
core  

Competing nonlinearities in quadratic nonlinear waveguide arrays

open access: yes, 2016
We demonstrate experimentally the existence of competing focusing and defocusing nonlinearities in a double-resonant system with quadratic nonlinear response.
Lederer, Falk   +5 more
core   +1 more source

Measurement of calcium isotopes (δ44Ca) using a multicollector TIMS technique [PDF]

open access: yes, 2002
We propose a new“multicollector technique” for the thermal ionization mass spectrometer (TIMS) measurement of calcium (Ca) isotope ratios improving average internal statistical uncertainty of the 44Ca/40Ca measurements by a factor of 2–4 and average ...
Bock, Barbara   +5 more
core   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Die Mulomedicina des Teodorico di Cervia. Neue Perspektiven mittels einer interdisziplinären Annäherung

open access: yesPallas, 2016
The Mulomedicina of Teodorico di Cervia is centered in an interdisciplinary project which is actually applied for at the Deutsche Forschungsgemeinschaft (DFG). According to our preliminary work in the last years it can be stated that the editions of Dolz,
Martina Schwarzenberger
doaj   +1 more source

Winding Number Transitions in the Mottola-Wipf Model on a Circle [PDF]

open access: yes, 2000
Winding number transitions from quantum to classical behavior are studied in the case of the {1+1} dimensional Mottola-Wipf model with the space coordinate on a circle for exploring the possibility of obtaining transitions of second order.
Arscott   +20 more
core   +2 more sources

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Choroidal Haller's and Sattler's Layer Thickness Measurement Using 3-Dimensional 1060-nm Optical Coherence Tomography [PDF]

open access: yes, 2014
Objectives: To examine the feasibility of automatically segmented choroidal vessels in three-dimensional (3D) 1060-nmOCT by testing repeatability in healthy and AMD eyes and by mapping Haller's and Sattler's layer thickness in healthy eyes Methods ...
Ansari-Shahrezaei, Siamak   +12 more
core   +3 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

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