Results 41 to 50 of about 77,988 (240)

The DFG National Research Collection System (Sondersammelgebietssystemplan -SSG) for Print and Electronic Publications

Liber Quarterly: The Journal of European Research Libraries, 2005
Germany (the sum of the sixteen states of the Federal Republic) is historically and politically a decentralized country. The influence of the states is very significant, particularly in cultural and educational affairs (Kulturhoheit der Länder).
Elmar Mittler
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Un seminario bilaterale italo-tedesco sulla coroplastica cretese

Les Carnets de l’ACoSt, 2014
Si è tenuto a Catania, dal 19 al 21 settembre del 2013, il seminario bilaterale italo-tedesco, dal titolo Pilina Eidolia. New Perspectives in Cretan Coroplastic Studies (13th–7th century B.C.), organizzato da Antonella Pautasso (IBAM-CNR) e da Oliver ...
Antonella Pautasso, Oliver Pilz
doaj   +1 more source

Prediction of depressive symptoms severity based on sleep quality, anxiety, and gray matter volume: a generalizable machine learning approach across three datasetsResearch in context

EBioMedicine
Summary: Background: Depressive symptoms are rising in the general population, but their associated factors are unclear. Although the link between sleep disturbances and depressive symptoms severity (DSS) is reported, the predictive role of sleep on DSS
Mahnaz Olfati, Fateme Samea, Shahrooz Faghihroohi, Somayeh Maleki Balajoo, Vincent Küppers, Sarah Genon, Kaustubh Patil, Simon B. Eickhoff, Masoud Tahmasian   +8 more
doaj   +1 more source

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann, Theresa Lüth, Susen Schaake, Carolin Gabbert, Marius Möller, Hauke Busch, Katja Lohmann, Jonas A. Gustafson, Danny E. Miller, Kensuke Daida, Manabu Funayama, Nobutaka Hattori, Samia Ben Sassi, Faycel Hentati, Matthew J. Farrer, Kristian K. Ullrich, Christine Klein, Joanne Trinh   +17 more
wiley   +1 more source

Machine learning and biological validation identify sphingolipids as potential mediators of paclitaxel-induced neuropathy in cancer patients

eLife
Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a serious therapy-limiting side effect of commonly used anticancer drugs. Previous studies suggest that lipids may play a role in CIPN.
Jörn Lötsch, Khayal Gasimli, Sebastian Malkusch, Lisa Hahnefeld, Carlo Angioni, Yannick Schreiber, Sandra Trautmann, Saskia Wedel, Dominique Thomas, Nerea Ferreiros Bouzas, Christian H Brandts, Benjamin Schnappauf, Christine Solbach, Gerd Geisslinger, Marco Sisignano   +14 more
doaj   +1 more source

Genetic Algorithm Embedded into a Quality-Oriented Workflow of Methods for the Development of a Linear Drive used in Intralogistic Systems

Archives of Electrical Engineering, 2014
This paper presents the results of the DFG-project (Deutsche Forschungsgemeinschaft) Q-ELF (“Qualitätsorientierter Methodenworkflow für die Produktneuentwicklung eines Linearantriebs in der Fördertechnik”) carried out in cooperation of the TU Dortmund ...
Wörner Linus, Kulig Stefan, Willing Marén, Winzer Petra   +3 more
doaj   +1 more source

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich, Jonathan A. Gernert, Hanna Zimmermann, Lisa Tagnin, Marianthi Zeinaki, Laura Sanzo, Letizia Vogler, Elisabeth Kaufmann, Justina Dargvainiene, Frank Leypoldt, Gérard N. Bischof, Robert Perneczky, Boris‐Stephan Rauchmann, Simon Lindner, Günter U. Höglinger, Rudolf A. Werner, Martin Kerschensteiner, Tania Kümpfel, Matthias Brendel, Franziska S. Thaler   +19 more
wiley   +1 more source

An Octave/MATLAB® Interface for Rapid Processing of SMOS L1C Full Polarization Brightness Temperature

Journal of Open Research Software, 2018
A tool to process the SMOS microwave radiometer level 1C polarized brightness temperatures data product has been developed. The SMOS L1C science product contains the dual and full (Stokes vector) polarization brightness temperatures at L-band for ...
Pablo Saavedra, Clemens Simmer
doaj   +1 more source