Results 141 to 150 of about 878,178 (411)

„Grundstein für Weiterentwicklung von Gesundheitsystemen”

open access: yesMonitor Versorgungsforschung
Prof. Dr. Oliver Gröne, Chief Scientific Officer und Leiter Forschung der OptiMedis AG sowie Mitglied des PaRIS-SUR-Konsortiums, geht davon aus, dass der OECD-Initiative „Patient-Reported Indicator Survey” (PaRIS) eine ähnliche Bedeutung wie das OECD ...
Prof. Dr. Oliver Gröne PhD MSc   +1 more
doaj   +1 more source

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

open access: yesMolecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau   +9 more
wiley   +1 more source

Internetpolitik in Deutschland

open access: yesTATuP - Zeitschrift für Technikfolgenabschätzung in Theorie und Praxis, 2005
Die Rahmenbedingungen nationalstaatlicher Technologiepolitik haben sich in den letzten 30 Jahren grundlegend geändert. Trotz der tendenziellen Erosion des klassischen Nationalstaats bestehen aber weiterhin Gestaltungsmöglichkeiten, die auch genutzt werden.
openaire   +4 more sources

Cross-border activities, taxation and the European single market. [PDF]

open access: yes
Grenzüberschreitender Verkehr; Konsumentenverhalten; Berufsverkehr; Direktinvestition; Steuerbelastung; Dänemark; Deutschland; Frankreich; Euregio Maas-Rhein;
Bode, Eckhardt   +2 more
core  

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

Reach of Globalization in 18th Century Germany: Atlantic Products from Hamburg to Saxon Markets

open access: yesJahrbuch für Wirtschaftsgeschichte
This study explores the economic cohesion of two German areas, Hamburg and Saxony, in the 18th century, created through the inflow of Atlantic colonial groceries from the former to the latter.
Kikuchi Yuta
doaj   +1 more source

Social Welfare Reform [PDF]

open access: yes
Wohlfahrtseffek, Sozialreform, Vergleich, Vereinigte Staaten, Deutschland, Welfare effect, Social reform, Comparison, United states ...
Hans-Werner Sinn
core  

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