Results 141 to 150 of about 683,224 (393)

Deutschlands Aussenpolitik von Bismarcks Abgang bis zum Ende des Weltkrieges [PDF]

, 1924
Sidney B. Fay, Veit Valentin
openalex   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

National Institutional Systems in Global Competition and the Inertia of German Labour Market Institutions [PDF]

Arbeitsverwaltung, Internationaler Wettbewerb, Deutschland, Welt, Labour administration, Global competition, Germany ...
Wolfgang Ochel
core  

Cavity Formation in Silica-Filled Rubber Compounds Observed During Deformation by Ultra Small-Angle X-Ray Scattering [PDF]

When silica-filled rubber compounds are deformed, structural modifications in the material's bulk lead to irreversible damage, the most significant of which is cavitation appearing within the interfaces of interconnected polymer and filler networks. This work introduces a new method to analyze cavitation in industrial-grade rubbers based on Ultra Small-
arxiv   +1 more source

Statistik der Aerzte in Deutschland [PDF]

, 1897
G. Heimann
openalex   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Paradigmen Kultureller Differenz und Hybriditaet

, 2004
About the book: Zwar ist in den letzten Jahren der Konsens gewachsen, dass Deutschland ein Einwanderungsland ist, aber der Blick auf Migranten hat sich dadurch nicht wesentlich geändert. Auf der Basis des Paradigmas kultureller Differenz gelten sie nach
Erel, Umut
core  

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

Molecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam   +8 more
wiley   +1 more source

A Concept for a New Budget Rule for Germany [PDF]

Öffentlicher Haushalt, Öffentliche Finanzplanung, Deutschland, Public Budget, Public Budgeting ...
Christian Kastrop, Elke Baumann, Elmar Dönnebrink   +2 more
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Studien zur Bevolkerungsbewegung in Deutschland in den Letzten Jahrzehnten mit Besonderen Berucksichtigung der Ehelichen Fruchtbarkeit. [PDF]

, 1907
G. Udny Yule, Paul Mombert
openalex   +1 more source