Results 81 to 90 of about 5,957,804 (303)
Diabetic retinopathy (DR), a leading cause of global blindness, represents a significant microvascular complication of diabetes mellitus. This comprehensive review examines the evolving landscape of monoclonal antibody (mAb) therapy in DR management. The
Yuan Zong +9 more
doaj +1 more source
Systematicity and surface similarity in the development of analogy [PDF]
This research investigates the development of analogy: In particular, we wish to study the development of systematicity in analogy. Systematicity refers to the mapping of systems of mutually constraining relations, such as causal chains or chains of implication. A preference for systematic mappings is a central aspect of analogical processing in adults
Gentner, Dedre, Toupin, Cecile
openaire +1 more source
Development of a high-sensitivity torsion balance to investigate the thermal Casimir force
We report development of a high-sensitivity torsion balance to measure the thermal Casimir force. Special emphasis is placed on experimental investigations of a possible surface electric force originating from surface patch potentials that have been ...
Casimir H. B. +7 more
core +1 more source
Direct Patterning of a Cyclotriveratrylene Derivative for Directed Self-assembly of C60 [PDF]
A novel apex-modified cyclotriveratrylene (CTV) derivative with an attached thiolane-containing lipoic acid linker was directly patterned onto gold substrates via dip-pen nanolithography (DPN).
Becker, Daniel P. +3 more
core +3 more sources
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Eimeria tenella protein trafficking: differential regulation of secretion versus surface tethering during the life cycle [PDF]
Eimeria spp. are intracellular parasites that have a major impact on poultry. Effective live vaccines are available and the development of reverse genetic technologies has raised the prospect of using Eimeria spp.
Blake, D P +4 more
core +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Mechanics of couple-stress fluid coatings [PDF]
The formal development of a theory of viscoelastic surface fluids with bending resistance - their kinematics, dynamics, and rheology are discussed. It is relevant to the mechanics of fluid drops and jets coated by a thin layer of immiscible fluid with ...
Waxman, A. M.
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Experimental Insights into Hydraulic Jump Roller Length: The Impact of Compound Geometry, Slope, and Bed Roughness [PDF]
This experimental investigation examines the relative roller length (Lr/h1) of hydraulic jumps taking place in composite rectangular channel featuring positive inclinations and roughened minor beds, aiming to address gaps in understanding the effects of ...
I. Herri +4 more
doaj +1 more source

