Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Thinking Outside the Box: Strategies and Examples for in the Preservation and Development of Heritage [PDF]
This paper present examples of positive economic and social impacts of cultural projects and mentions an interpretation of the positive interaction between development and culture.
Inter-American Development Bank
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Country Program Evaluation: Ecuador (2000-2006)
This report (RE-341) presents the Office of Evaluation and Oversight\u27s country program evaluation (CPE) assessing the Bank\u27s Ecuador program in 2000-2006. The present CPE takes in the Bank programming exercises charted in the country strategies for
Inter-American Development Bank
core +1 more source
Recommendations and Best Practices on Taxation of SMEs in Latin America [PDF]
This presentation explores the economic, institutional and technological contexts in which micro, small and medium enterprises (SMEs) are called upon to operate and the fiscal treatment issues public authorities should take into account.
Inter-American Development Bank
core +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Country Program Evaluation: Brazil (2000-2008)
This Country Program Evaluation (RE-355) analyzes the recent performance of the Bank\u27s portfolio of operations. Two country strategies were approved during 2000-2008, which were prepared in two very different contexts in Brazil. The 2000-2003 strategy
Inter-American Development Bank
core +1 more source
Priorities and Strategies in Rural Poverty Reduction: Experiences from Latin America and Asia [PDF]
This publication is part of a series of books on comparative best practices in social development between Latin America and the Caribbean and East Asia undertaken by the Institute for Social Development (INDES) and the Japan Program of the Inter-American
Inter-American Development Bank
core +1 more source
Between Finance and Growth: The Role of Financial Development in Promoting Economic growth in Africa
Purpose: This study investigates the impact of financial development on economic growth, with a particular focus on the roles of financial institutions' access, depth, and efficiency.
Boulenouar Ilias Zakaria Mennad +2 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source

