Results 141 to 150 of about 1,509,136 (297)

Analysis of the spatial and temporal evolution process and development trend of innovation capability of Chinese sports industry. [PDF]

PLoS One, 2023
Chen J, Cai C, Zhang T.
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Issue Analysis of Large Scale Fracturing Equipment Application and Its Development Trend

Shiyou jixie, 2017
In the process of domestic shale gas development, large-scale fracturing equipment have common applications issues like low power utilization and unreasonable equipment application.
Wu Hanchuan
doaj  

Research status and development trend of extracorporeal membrane oxygenation based on bibliometrics. [PDF]

Front Cardiovasc Med, 2023
Guan C, Shen H, Dong S, Zhan Y, Yang J, Zhang Q, Wang R.   +6 more
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Retracted: Construction of Prediction Model of Ecological Forestry Economic Development Trend Based on Deep Belief Network. [PDF]

Comput Intell Neurosci, 2023
Intelligence And Neuroscience C.
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Drilling Parameters Optimization Technology Status and Development Trend

Shiyou jixie, 2016
With the increasing complex conditions for offshore and underground exploitation,and the continuous development of drilling technology,tools,equipment and instrumentation technology,the corresponding monitoring while drilling technology and computer ...
Sha Linxiu
doaj  

Personalized intrahepatic cholangiocarcinoma prognosis prediction using radiomics: Application and development trend. [PDF]

Front Oncol, 2023
Chen P, Yang Z, Zhang H, Huang G, Li Q, Ning P, Yu H.   +6 more
europepmc   +1 more source

Temporary teachers in Latin America and the Caribbean [PDF]

This study delves into the growing trend of hiring temporary teachers in Latin America and the Caribbean (LAC), driven by the need for education systems to find more cost-effective and flexible solutions in the face of budget constraints and increasing ...
Inter-American Development Bank
core   +1 more source