Results 141 to 150 of about 17,112,399 (298)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

IDB America: Vol. 26, no. 11-12, November-December 1999

open access: yes, 1999
IDB America reports on economic and social development trends in Latin America and the Caribbean and on the activities of the IDB.
Inter-American Development Bank
core   +1 more source

Drilling Parameters Optimization Technology Status and Development Trend

open access: yesShiyou jixie, 2016
With the increasing complex conditions for offshore and underground exploitation,and the continuous development of drilling technology,tools,equipment and instrumentation technology,the corresponding monitoring while drilling technology and computer ...
Sha Linxiu
doaj  

Research status and development trend of extracorporeal membrane oxygenation based on bibliometrics. [PDF]

open access: yesFront Cardiovasc Med, 2023
Guan C   +6 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

IDB America: Vol. 25, no. 1-2, January-February 1998

open access: yes, 1998
IDB America reports on economic and social development trends in Latin America and the Caribbean and on the activities of the IDB.
Inter-American Development Bank
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

IDB News: Vol. 3, no. 1, February 1976

open access: yes, 1976
IDB News is a monthly publication of the Inter-American Development Bank and appears in English and Spanish ...
Inter-American Development Bank
core   +1 more source

Home - About - Disclaimer - Privacy