Results 21 to 30 of about 174,744 (236)
The International Journal of Developmental Biology, 2009 In this article we will discuss the integration of developmental patterning mechanisms with waves of competency that control the ability of a homogeneous field of cells to react to pattern forming cues and generate spatially heterogeneous patterns.
Baker, R, Schnell, S, Maini, P
openaire +4 more sources
Distinct regulatory mechanisms act to establish and maintain Pax3 expression in the developing neural tube. [PDF]
PLoS Genetics, 2013 Pattern formation in developing tissues is driven by the interaction of extrinsic signals with intrinsic transcriptional networks that together establish spatially and temporally restricted profiles of gene expression. How this process is orchestrated at
Steven Moore +5 more
doaj +1 more source
Diversity in the Development of the Neuromuscular System of Nemertean Larvae (Nemertea, Spiralia)
Frontiers in Ecology and Evolution, 2021 In studies on the development of nervous systems and musculature, fluorescent labeling of neuroactive substances and filamentous actin (f-actin) of muscle cells and the subsequent analysis with confocal laser scanning microscopy (CLSM), has led to a ...
Jörn von Döhren
doaj +1 more source
Embryonic and foetal expression patterns of the ciliopathy gene CEP164.
PLoS ONE, 2020 Nephronophthisis-related ciliopathies (NPHP-RC) are a group of inherited genetic disorders that share a defect in the formation, maintenance or functioning of the primary cilium complex, causing progressive cystic kidney disease and other clinical ...
L A Devlin +8 more
doaj +1 more source
Physiological inputs regulate species-specific anatomy during embryogenesis and regeneration
Communicative & Integrative Biology, 2016 A key problem in evolutionary developmental biology is identifying the sources of instructive information that determine species-specific anatomical pattern.
Kelly G. Sullivan +2 more
doaj +1 more source
F1000Research, 2017 In the rat testis, studies have shown that cell polarity, in particular spermatid polarity, to support spermatogenesis is conferred by the coordinated efforts of the Par-, Crumbs-, and Scribble-based polarity complexes in the seminiferous epithelium ...
Linxi Li +8 more
doaj +1 more source
Mad is required for wingless signaling in wing development and segment patterning in Drosophila.
PLoS ONE, 2009 A key question in developmental biology is how growth factor signals are integrated to generate pattern. In this study we investigated the integration of the Drosophila BMP and Wingless/GSK3 signaling pathways via phosphorylations of the transcription ...
Edward Eivers +5 more
doaj +1 more source
Molecular bioelectricity in developmental biology: New tools and recent discoveries [PDF]
BioEssays, 2012 AbstractSignificant progress in the molecular investigation of endogenous bioelectric signals during pattern formation in growing tissues has been enabled by recently developed techniques. Ion flows and voltage gradients produced by ion channels and pumps are key regulators of cell proliferation, migration, and differentiation.
openaire +2 more sources
Chick fetal organ spheroids as a model to study development and disease
BMC Molecular and Cell Biology, 2021 Background Organ culture models have been used over the past few decades to study development and disease. The in vitro three-dimensional (3D) culture system of organoids is well known, however, these 3D systems are both costly and difficult to culture ...
Soran Dakhel +5 more
doaj +1 more source
Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas
Pediatric Blood &Cancer, EarlyView.ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall +2 more
wiley +1 more source