Results 41 to 50 of about 201,067 (302)
The evolution of developmental biology through conceptual and technological revolutions.
CellDevelopmental biology-the study of the processes by which cells, tissues, and organisms develop and change over time-has entered a new golden age. After the molecular genetics revolution in the 80s and 90s and the diversification of the field in the ...
Prisca Liberali, Alexander F. Schier
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Variational system identification of the partial differential equations governing the physics of pattern-formation: Inference under varying fidelity and noise [PDF]
Computer Methods in Applied Mechanics and Engineering, 2018 We present a contribution to the field of system identification of partial differential equations (PDEs), with emphasis on discerning between competing mathematical models of pattern-forming physics. The motivation comes from developmental biology, where
Zhenlin Wang, X. Huan, K. Garikipati
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FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
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Scientific Reports, 2023 The Japanese rhinoceros beetle Trypoxylus dichotomus is a giant beetle with distinctive exaggerated horns present on the head and prothoracic regions of the male. T.
Shinichi Morita +21 more
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Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
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Theoretical and experimental approaches to understand morphogen gradients
Molecular Systems Biology, 2008 Morphogen gradients, which specify different fates for cells in a direct concentration‐dependent manner, are a highly influential framework in which pattern formation processes in developmental biology can be characterized.
Marta Ibañes +1 more
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Probing three-dimensional collective cancer invasion with DIGME
Cancer Convergence, 2017 Background Multicellular pattern formation plays an important role in developmental biology, cancer metastasis and wound healing. While many physical factors have been shown to regulate these multicellular processes, the role of ECM micro-to-meso scale ...
Amani A. Alobaidi, Bo Sun
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Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
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Integument pattern formation involves genetic and epigenetic controls: feather arrays simulated by digital hormone models [PDF]
, 2004 Pattern formation is a fundamental morphogenetic process. Models based on genetic and epigenetic control have been proposed but remain controversial. Here we use feather morphogenesis for further evaluation.
정한성
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Effects of multistability, absorbing boundaries and growth on Turing pattern formation
bioRxivTuring patterns are a fundamental concept in developmental biology, describing how homogeneous tissues develop into self-organized spatial patterns.
M. Oliver Huidobro, Robert G. Endres
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