Results 51 to 60 of about 445,283 (270)

Unravelling the genes forming the wing pattern supergene in the polymorphic butterfly Heliconius numata

open access: yesEvoDevo, 2019
Background Unravelling the genetic basis of polymorphic characters is central to our understanding of the origins and diversification of living organisms.
Suzanne V. Saenko   +5 more
doaj   +1 more source

Agrobacterium tumefaciens mediated transformation of the aquatic carnivorous plant Utricularia gibba

open access: yesPlant Methods, 2020
Background The genus Utricularia belongs to Lentibulariaceae, the largest family of carnivorous plants, which includes terrestrial, epiphytic and aquatic species.
A. Oropeza-Aburto   +3 more
doaj   +1 more source

Thyroid hormone regulates distinct paths to maturation in pigment cell lineages [PDF]

open access: yes, 2019
Thyroid hormone (TH) regulates diverse developmental events and can drive disparate cellular outcomes. In zebrafish, TH has opposite effects on neural crest derived pigment cells of the adult stripe pattern, limiting melanophore population expansion, yet
Aman, Andrew J   +10 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Reaction-diffusion pattern in shoot apical meristem of plants. [PDF]

open access: yesPLoS ONE, 2011
A fundamental question in developmental biology is how spatial patterns are self-organized from homogeneous structures. In 1952, Turing proposed the reaction-diffusion model in order to explain this issue.
Hironori Fujita   +3 more
doaj   +1 more source

In silico transitions to multicellularity

open access: yes, 2014
The emergence of multicellularity and developmental programs are among the major problems of evolutionary biology. Traditionally, research in this area has been based on the combination of data analysis and experimental work on one hand and theoretical ...
Duran-Nebreda, Salva, Solé, Ricard V.
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Specific Eph receptor-cytoplasmic effector signaling mediated by SAM–SAM domain interactions

open access: yeseLife, 2018
The Eph receptor tyrosine kinase (RTK) family is the largest subfamily of RTKs playing critical roles in many developmental processes such as tissue patterning, neurogenesis and neuronal circuit formation, angiogenesis, etc.
Yue Wang   +7 more
doaj   +1 more source

Intrinsic noise profoundly alters the dynamics and steady state of morphogen-controlled bistable genetic switches [PDF]

open access: yes, 2016
During tissue development, patterns of gene expression determine the spatial arrangement of cell types. In many cases, gradients of secreted signaling molecules - morphogens - guide this process.
Briscoe, James   +3 more
core   +5 more sources

Home - About - Disclaimer - Privacy