Results 61 to 70 of about 201,067 (302)

Spatiotemporal pattern formation in early development: A review of primitive streak formation and somitogenesis

open access: yes, 2000
The basic body plan of a number of vertebrates results from two processes that occur early in the development of the blastoderm: large scale rearrangements of tissue via a process called gastrulation, and axial subdivision of tissue in a process called ...
Maini, P K   +15 more
core   +1 more source

Unravelling the genes forming the wing pattern supergene in the polymorphic butterfly Heliconius numata

open access: yesEvoDevo, 2019
Background Unravelling the genetic basis of polymorphic characters is central to our understanding of the origins and diversification of living organisms.
Suzanne V. Saenko   +5 more
doaj   +1 more source

Agrobacterium tumefaciens mediated transformation of the aquatic carnivorous plant Utricularia gibba

open access: yesPlant Methods, 2020
Background The genus Utricularia belongs to Lentibulariaceae, the largest family of carnivorous plants, which includes terrestrial, epiphytic and aquatic species.
A. Oropeza-Aburto   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Reaction-diffusion pattern in shoot apical meristem of plants. [PDF]

open access: yesPLoS ONE, 2011
A fundamental question in developmental biology is how spatial patterns are self-organized from homogeneous structures. In 1952, Turing proposed the reaction-diffusion model in order to explain this issue.
Hironori Fujita   +3 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Specific Eph receptor-cytoplasmic effector signaling mediated by SAM–SAM domain interactions

open access: yeseLife, 2018
The Eph receptor tyrosine kinase (RTK) family is the largest subfamily of RTKs playing critical roles in many developmental processes such as tissue patterning, neurogenesis and neuronal circuit formation, angiogenesis, etc.
Yue Wang   +7 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Multimodal transcriptional control of pattern formation in embryonic development

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2019
Significance Predicting how the gene expression patterns that specify animal body plans arise from interactions between transcription factor proteins and regulatory DNA remains a major challenge in physical biology.
Nicholas C. Lammers   +5 more
semanticscholar   +1 more source

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