Results 1 to 10 of about 445,854 (255)
Molecular Mechanisms of Developmental Timing in C. elegans and Drosophila [PDF]
Developmental Cell, 2001 Characterization of the heterochronic genes has provided a strong foundation for understanding the molecular mechanisms of developmental timing in C. elegans. In apparent contrast, studies of developmental timing in Drosophila have demonstrated a central role for gene cascades triggered by the steroid hormone ecdysone.
Carl Thummel
exaly +3 more sources
Evolution and molecular mechanisms of adaptive developmental plasticity [PDF]
Molecular Ecology, 2011 AbstractAside from its selective role in filtering inter‐individual variation during evolution by natural selection, the environment also plays an instructive role in producing variation during development. External environmental cues can influence developmental rates and/or trajectories and lead to the production of distinct phenotypes from the same ...
Patricia Beldade, Roberto A Keller
exaly +3 more sources
Open Biology, 2022 Developmental signalling pathways such as Wnt/β-catenin, Notch and Sonic hedgehog play a central role in nearly all the stages of neuronal development. The term ‘embryonic’ might appear to be a misnomer to several people because these pathways are functional during the early stages of embryonic development and adulthood, albeit to a certain degree ...
Rohit Gundamaraju +2 more
exaly +8 more sources
Pediatric Hepatoblastoma: From Developmental Molecular Mechanisms to Innovative Therapeutic Strategies. [PDF]
Cancers (Basel)Background/Objectives: Hepatoblastoma, the most common pediatric primary liver cancer, is no longer regarded as a conventional malignancy but rather as a tumor emerging from disrupted hepatic developmental processes. Although improvements in chemotherapy, surgical techniques, and liver transplantation have markedly enhanced survival, therapeutic ...
Scurtu AM +10 more
europepmc +4 more sources
Molecular mechanisms and genetic factors contributing to the developmental dysplasia of the hip
Frontiers in GeneticsThe most prevalent hip disease in neonates is developmental dysplasia of the hip (DDH). A timely and accurate diagnosis is required to provide the most effective treatment for pediatric patients with DDH. Heredity and gene variation have been the subject of increased attention and research worldwide as one of the factors contributing to the ...
Yang Zhonghua
exaly +4 more sources
Harmony in the Molecular Orchestra of Hearing: Developmental Mechanisms from the Ear to the Brain
Annual Review of NeuroscienceAuditory processing in mammals begins in the peripheral inner ear and extends to the auditory cortex. Sound is transduced from mechanical stimuli into electrochemical signals of hair cells, which relay auditory information via the primary auditory neurons to cochlear nuclei. Information is subsequently processed in the superior olivary complex, lateral
Bernd Fritzsch +2 more
exaly +4 more sources
Editorial: Circuit, molecular, and developmental mechanisms in decision-making behavior
Frontiers in Neuroscience, 2023 Tom Macpherson +3 more
doaj +3 more sources
Developmental roles and molecular mechanisms of Asterix/GTSF1 [PDF]
WIREs RNA, 2022 AbstractMaintenance of germline genomic integrity is critical for the survival of animal species. Consequently, many cellular and molecular processes have evolved to ensure genetic stability during the production of gametes. Here, we describe the discovery, characterization, and emerging molecular mechanisms of the protein Asterix/Gametocyte‐specific ...
Jonathan J. Ipsaro, Leemor Joshua‐Tor
openaire +2 more sources
Molecular mechanisms of midfacial developmental defects [PDF]
Developmental Dynamics, 2015 The morphogenesis of midfacial processes requires the coordination of a variety of cellular functions of both mesenchymal and epithelial cells to develop complex structures. Any failure or delay in midfacial development as well as any abnormal fusion of the medial and lateral nasal and maxillary prominences will result in developmental defects in the ...
Akiko, Suzuki +3 more
openaire +2 more sources
Sub-centrosomal mapping identifies augmin-γTuRC as part of a centriole-stabilizing scaffold
Nature Communications, 2021 The γ-tubulin ring complex (γTuRC) nucleates microtubules at the centrosome, but how this function is related to γTuRC subcentrosomal distribution is unclear.
Nina Schweizer +6 more
doaj +1 more source