Results 1 to 10 of about 822,905 (187)
Genetic screen in Drosophila muscle identifies autophagy-mediated T-tubule remodeling and a Rab2 role in autophagy [PDF]
eLife, 2017 Transverse (T)-tubules make-up a specialized network of tubulated muscle cell membranes involved in excitation-contraction coupling for power of contraction. Little is known about how T-tubules maintain highly organized structures and contacts throughout
Naonobu Fujita +10 more
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Editorial: Circuit, molecular, and developmental mechanisms in decision-making behavior
Frontiers in Neuroscience, 2023 Tom Macpherson +3 more
doaj +3 more sources
Developmental roles and molecular mechanisms of Asterix/GTSF1 [PDF]
WIREs RNA, 2022 AbstractMaintenance of germline genomic integrity is critical for the survival of animal species. Consequently, many cellular and molecular processes have evolved to ensure genetic stability during the production of gametes. Here, we describe the discovery, characterization, and emerging molecular mechanisms of the protein Asterix/Gametocyte‐specific ...
Jonathan J. Ipsaro, Leemor Joshua‐Tor
openaire +3 more sources
Molecular mechanisms of midfacial developmental defects [PDF]
Developmental Dynamics, 2015 The morphogenesis of midfacial processes requires the coordination of a variety of cellular functions of both mesenchymal and epithelial cells to develop complex structures. Any failure or delay in midfacial development as well as any abnormal fusion of the medial and lateral nasal and maxillary prominences will result in developmental defects in the ...
Akiko, Suzuki +3 more
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Sub-centrosomal mapping identifies augmin-γTuRC as part of a centriole-stabilizing scaffold
Nature Communications, 2021 The γ-tubulin ring complex (γTuRC) nucleates microtubules at the centrosome, but how this function is related to γTuRC subcentrosomal distribution is unclear.
Nina Schweizer +6 more
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Evolution and molecular mechanisms of adaptive developmental plasticity [PDF]
Molecular Ecology, 2011 AbstractAside from its selective role in filtering inter‐individual variation during evolution by natural selection, the environment also plays an instructive role in producing variation during development. External environmental cues can influence developmental rates and/or trajectories and lead to the production of distinct phenotypes from the same ...
Patrícia, Beldade +2 more
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Molecular mechanisms of developmentally programmed crinophagy in Drosophila [PDF]
Journal of Cell Biology, 2017 At the onset of metamorphosis, Drosophila salivary gland cells undergo a burst of glue granule secretion to attach the forming pupa to a solid surface. Here, we show that excess granules evading exocytosis are degraded via direct fusion with lysosomes, a secretory granule-specific autophagic process known as crinophagy.
Tamás Csizmadia +5 more
openaire +3 more sources
Epigenetic control of melanoma cell invasiveness by the stem cell factor SALL4
Nature Communications, 2021 Melanoma cells can switch between proliferative and invasive phenotypes. Here the authors show that the embryonic stem cell factor Sall4 is a negative regulator of melanoma phenotype switching where its loss leads to the acquisition of an invasive ...
Johanna Diener +16 more
doaj +1 more source
The regulation of Hox gene expression during animal development [PDF]
, 2013 Hox genes encode a family of transcriptional regulators that elicit distinct developmental programmes along the head-to-tail axis of animals. The specific regional functions of individual Hox genes largely reflect their restricted expression patterns ...
Alonso, Claudio R, Mallo, Moisés
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Plant responses to photoperiod [PDF]
, 2009 Photoperiod controls many developmental responses in animals, plants and even fungi. The response to photoperiod has evolved because daylength is a reliable indicator of the time of year, enabling developmental events to be scheduled to coincide with ...
Abe +154 more
core +1 more source