Results 21 to 30 of about 7,143,981 (292)

Epigenetic control of melanoma cell invasiveness by the stem cell factor SALL4

Nature Communications, 2021
Melanoma cells can switch between proliferative and invasive phenotypes. Here the authors show that the embryonic stem cell factor Sall4 is a negative regulator of melanoma phenotype switching where its loss leads to the acquisition of an invasive ...
Johanna Diener, Arianna Baggiolini, Mattias Pernebrink, Damian Dalcher, Luigi Lerra, Phil F. Cheng, Sandra Varum, Jessica Häusel, Salome Stierli, Mathias Treier, Lorenz Studer, Konrad Basler, Mitchell P. Levesque, Reinhard Dummer, Raffaella Santoro, Claudio Cantù, Lukas Sommer   +16 more
doaj   +1 more source

How Developmental is Evolutionary Developmental Biology? [PDF]

, 2002
Evolutionary developmental biology (evo-devo) offers both an account of developmental processes and also new integrative frameworks for analyzing interactions between development and evolution.
Jason Scott Robert, Robert, Jason Scott
core   +1 more source

Non-alcoholic Fatty pancreas disease pathogenesis: a role for developmental programming and altered circadian rhythms. [PDF]

, 2014
Emerging evidence suggests that maternal obesity (MO) predisposes offspring to obesity and the recently described non-alcoholic fatty pancreas disease (NAFPD) but involved mechanisms remain unclear.
Mouralidarane Angelina, Chiara Saracino, Lucilla Poston (200809), Francesca Rappa, Ruma Saraswati, Fusai, Giuseppe, Paul D. Taylor (200813), Pazienza Valerio, Junpei Soeda, Carter, Rebeca, Jude A Oben, Angelina Mouralidarane (540950), Saraswati Ruma, Paul D Taylor, Mouralidarane, Angelina, Oben, JA, Saraswati, R, Fusai Giuseppe, Marco Novelli, Carter, R, Poston Lucilla, Marco Novelli (540954), Giuseppe Fusai (540955), Shuvra Ray (540951), Soeda, Junpei, Soeda, J, Pombo, J, Mouralidarane, A, Rappa, F, Ruma Saraswati (540953), Pazienza, Valerio, Novelli, Marco, Taylor Paul D., Joaquim Pombo (540952), Carter Rebeca, Saracino, C, Manlio Vinciguerra (287299), Saraswati, Ruma, Novelli, M, Oben, Jude A, Angelina Mouralidarane, Pombo, Joaquim, Fusai, G, RAPPA, Francesca, Saracino, Chiara, Novelli Marco, Rappa Francesca, Lucilla Poston, Francesca Rappa (55683), Manlio Vinciguerra, Rebeca Carter, Saracino Chiara, Poston, Lucilla; id_orcid, Pazienza, V, Vinciguerra, M, Joaquim Pombo, Rebeca Carter (540949), Ray Shuvra, Vinciguerra, Manlio, Vinciguerra, M. Oben J.A., Junpei Soeda (453348), Valerio Pazienza, Poston, L, Vinciguerra Manlio, Ray, S, Jude A. Oben (453352), Taylor, PD, Soeda Junpei, Giuseppe Fusai, Oben Jude A., Pombo Joaquim, Valerio Pazienza (174196), Taylor, Paul D; id_orcid, Chiara Saracino (540956), Ray, Shuvra, Shuvra Ray   +75 more
core   +1 more source

Neural stem cells in Drosophila : molecular genetic mechanisms underlying normal neural proliferation and abnormal brain tumor formation [PDF]

, 2012
Neural stem cells in Drosophila are currently one of the best model systems for understanding stem cell biology during normal development and during abnormal development of stem cell-derived brain tumors.
Heinrich Reichert, Reichert, Heinrich, Saini, Nidhi, Nidhi Saini   +3 more
core   +1 more source

From early markers to neuro-developmental mechanisms of autism [PDF]

, 2014
A fast growing field, the study of infants at risk because of having an older sibling with autism (i.e. infant sibs) aims to identify the earliest signs of this disorder, which would allow for earlier diagnosis and intervention.
Jones, Emily J.H., Johnson, Mark H., Johnson, M.H., Charman, T., Charman, T.; id_orcid, Johnson, M. H., Jones, E J H, Gliga, Teodora, Johnson, M H, Bedford, R., Jones, E.J.H., Gliga, T., Gliga, T, Charman, T, Bedford, R   +14 more
core   +1 more source

The Ingredients for a Postgenomic Synthesis of Nature and Nurture [PDF]

, 2008
This paper serves as an introduction to the special issue on “Reconciling Nature and Nurture in Behavior and Cognition Research” and sets its agenda to resolve the ‘interactionist’ dichotomy of nature as the genetic, and stable, factors of development ...
Stotz, Karola, Karola Stotz
core   +1 more source

Cellular and molecular studies of postembryonic muscle fibre recruitment in zebrafish (Danio rerio L.) [PDF]

, 2010
Cellular and molecular mechanisms of postembryonic muscle fibre recruitment were investigated in zebrafish (Danio rerio L.), a standard animal model for developmental and genetic studies.
Lee, Hung-Tai
core   +2 more sources

Subdivisions of the adult zebrafish pallium based on molecular marker analysis [version 2; referees: 2 approved, 1 approved with reservations]

F1000Research, 2015
Background: The telencephalon shows a remarkable structural diversity among vertebrates. In particular, the everted telencephalon of ray-finned fishes has a markedly different morphology compared to the evaginated telencephalon of all other vertebrates ...
Julia Ganz, Volker Kroehne, Dorian Freudenreich, Anja Machate, Michaela Geffarth, Ingo Braasch, Jan Kaslin, Michael Brand   +7 more
doaj   +1 more source

Novel targets of miR-30, a microRNA required for biliary development [v1; ref status: indexed, http://f1000r.es/1so]

F1000Research, 2013
MicroRNAs have been found to play a profound role in embryonic and post-natal development through their regulation of processes such as cell proliferation, differentiation, and morphogenesis.
Claire L. Le Guen, Joshua R. Friedman, Nicholas J. Hand   +2 more
doaj   +1 more source

Protocol for the visualization of pRps6-positive cells in larval zebrafish brains using whole-mount immunofluorescence and light-sheet microscopy

STAR Protocols
Summary: Due to their small size and transparency, larval zebrafish are a useful model for whole-brain imaging. Here, we present a protocol for the visualization of phosphorylated Rps6, a marker of mechanistic target of rapamycin complex 1 (mTORC1 ...
Olga Doszyn, Tomasz Dulski, Justyna Zmorzynska   +2 more
doaj   +1 more source