Results 11 to 20 of about 7,143,981 (292)
Molecular Mechanisms of Developmental Timing in C. elegans and Drosophila [PDF]
Developmental Cell, 2001 Characterization of the heterochronic genes has provided a strong foundation for understanding the molecular mechanisms of developmental timing in C. elegans. In apparent contrast, studies of developmental timing in Drosophila have demonstrated a central role for gene cascades triggered by the steroid hormone ecdysone.
Carl S Thummel
exaly +5 more sources
Open Biology, 2022 Developmental signalling pathways such as Wnt/β-catenin, Notch and Sonic hedgehog play a central role in nearly all the stages of neuronal development. The term ‘embryonic’ might appear to be a misnomer to several people because these pathways are functional during the early stages of embryonic development and adulthood, albeit to a certain degree ...
Rohit Gundamaraju +2 more
exaly +8 more sources
Pediatric Hepatoblastoma: From Developmental Molecular Mechanisms to Innovative Therapeutic Strategies. [PDF]
Cancers (Basel)Background/Objectives: Hepatoblastoma, the most common pediatric primary liver cancer, is no longer regarded as a conventional malignancy but rather as a tumor emerging from disrupted hepatic developmental processes. Although improvements in chemotherapy, surgical techniques, and liver transplantation have markedly enhanced survival, therapeutic ...
Scurtu AM +10 more
europepmc +4 more sources
Editorial: Circuit, molecular, and developmental mechanisms in decision-making behavior
Frontiers in Neuroscience, 2023 Tom Macpherson +3 more
doaj +3 more sources
Developmental roles and molecular mechanisms of Asterix/GTSF1 [PDF]
WIREs RNA, 2022 AbstractMaintenance of germline genomic integrity is critical for the survival of animal species. Consequently, many cellular and molecular processes have evolved to ensure genetic stability during the production of gametes. Here, we describe the discovery, characterization, and emerging molecular mechanisms of the protein Asterix/Gametocyte‐specific ...
Jonathan J. Ipsaro, Leemor Joshua‐Tor
openaire +2 more sources
A developmental perspective on developmental instability:Theory, models and mechanisms
, 2003 Although the terminology used in studies of developmental instability refers explicitly to development, this field of research has largely existed in isolation from mainstream developmental biology.
Klingenberg, CP; id_orcid
core +10 more sources
Molecular mechanisms of midfacial developmental defects [PDF]
Developmental Dynamics, 2015 The morphogenesis of midfacial processes requires the coordination of a variety of cellular functions of both mesenchymal and epithelial cells to develop complex structures. Any failure or delay in midfacial development as well as any abnormal fusion of the medial and lateral nasal and maxillary prominences will result in developmental defects in the ...
Akiko, Suzuki +3 more
openaire +2 more sources
Evolution and molecular mechanisms of adaptive developmental plasticity [PDF]
Molecular Ecology, 2011 AbstractAside from its selective role in filtering inter‐individual variation during evolution by natural selection, the environment also plays an instructive role in producing variation during development. External environmental cues can influence developmental rates and/or trajectories and lead to the production of distinct phenotypes from the same ...
Patrícia, Beldade +2 more
openaire +2 more sources
Sub-centrosomal mapping identifies augmin-γTuRC as part of a centriole-stabilizing scaffold
Nature Communications, 2021 The γ-tubulin ring complex (γTuRC) nucleates microtubules at the centrosome, but how this function is related to γTuRC subcentrosomal distribution is unclear.
Nina Schweizer +6 more
doaj +1 more source
Molecular mechanisms of developmentally programmed crinophagy in Drosophila [PDF]
Journal of Cell Biology, 2017 At the onset of metamorphosis, Drosophila salivary gland cells undergo a burst of glue granule secretion to attach the forming pupa to a solid surface. Here, we show that excess granules evading exocytosis are degraded via direct fusion with lysosomes, a secretory granule-specific autophagic process known as crinophagy.
Tamás Csizmadia +5 more
openaire +4 more sources