Results 31 to 40 of about 823,004 (286)

Developmental gene regulatory networks in sea urchins and what we can learn from them [version 1; referees: 3 approved]

F1000Research, 2016
Sea urchin embryos begin zygotic transcription shortly after the egg is fertilized.  Throughout the cleavage stages a series of transcription factors are activated and, along with signaling through a number of pathways, at least 15 different cell types ...
Megan L. Martik, Deirdre C. Lyons, David R. McClay   +2 more
doaj   +1 more source

Protocol for the visualization of pRps6-positive cells in larval zebrafish brains using whole-mount immunofluorescence and light-sheet microscopy

STAR Protocols
Summary: Due to their small size and transparency, larval zebrafish are a useful model for whole-brain imaging. Here, we present a protocol for the visualization of phosphorylated Rps6, a marker of mechanistic target of rapamycin complex 1 (mTORC1 ...
Olga Doszyn, Tomasz Dulski, Justyna Zmorzynska   +2 more
doaj   +1 more source

Molecular and cellular mechanisms underlying the evolution of form and function in the amniote jaw. [PDF]

, 2019
The amniote jaw complex is a remarkable amalgamation of derivatives from distinct embryonic cell lineages. During development, the cells in these lineages experience concerted movements, migrations, and signaling interactions that take them from their ...
A Abzhanov, A Abzhanov, A Abzhanov, A Baggiolini, A Baroffio, A Beverdam, A Chevallier, A Davidian, A del Rio, A Graham, A Graham, A Hosseini, A Rinon, A Roycroft, A Sharir, A Shellard, A Subramanian, AA Pitsillides, AE Adams, AE Merrill, AG Robling, AG Robling, AH Jheon, AJ Hughes, AL Romanoff, AL Tavares, ALP Tavares, AM Bailleul, AM Bailleul, AM Lucas, AS Pollard, AS Romer, AS Romer, AS Tucker, AS Tucker, AW Crompton, AW Crompton, B Christ, B McBratney-Owen, B Ruhin, BA Moore-Scott, BD Matthews, BF Eames, BF Eames, BF Kingsbury, BK Hall, BK Hall, BK Hall, BK Hall, BK Hall, BK Hall, BK Hall, BK Hall, BK Hall, BK Hall, BK Hall, BL Pruitt, C Attanasio, C Gans, C Gegenbaur, C Holliday, C Mitgutsch, C Patterson, C Reichert, CI Lorda-Diez, CL Hammond, CS Le Lievre, CS Le Lièvre, CT Miller, CV Baker, CV Baker, CW Benkman, CW Benkman, D Hu, D Hu, D Hu, D Hu, D Noden, DD Davis, DE Clouthier, DG Wilkinson, DJ Evans, DL Stemple, DM Noden, DM Noden, DM Noden, DM Noden, DM Noden, DM Noden, DM Noden, DM Noden, DM Noden, DM Noden, DM Noden, DM Noden, DR Carter, DR Cordero, E Berthet, E Blitz, E Blitz, E Dupin, E Gaupp, E Jarvik, E Theveneau, E Tzahor, E Tzahor, E Zelzer, EC Olesnicky Killian, EF Allin, EL Ealba, EM Sefton, EP Allis, EP Allis, EP Allis, ER Lankester, ES Goodrich, ES Goodrich, ES Russell, F Lescroart, F Liu, FJ Smith, FL Landacre, FV Jotereau, FW Chamberlain, G Andres, G Balooch, G Couly, G Couly, G Couly, G Kardon, G Kardon, G Köntges, G Wagner, G Zweers, GA Zweers, GA Zweers, GA Zweers, GB Muller, GF Couly, GF Couly, GM Morriss-Kay, GR de Beer, GR de Beer, GR de Beer, H Vinkka, HB Shaffer, HJ Chong, HL Hamilton, HL Szabo-Rogers, HP Shih, I Bothe, I Raizman, I Rot-Nikcevic, J Apostolakos, J Fang, J Grenier, J Hall, J Jeong, J Kahn, J Ruberte, J Stutzmann, JA Helms, JB Gross, JB Platt, JF Webb, JJ Baumel, JJ Schoenebeck, JJ Schoenebeck, JL Chang, JL Fish, JL Fish, JL Fish, JL Fish, JM Brito, JM Richman, JM Tabler, JN Thompson, JP Golding, JR Merida-Velasco, JR Merida-Velasco, JR Robbins, JS Kingsley, JW Kingsbury, K Hayashi, K Sheehan-Rooney, K Yasui, KC Woronowicz, KC Wu, KE Haworth, KJ Lamb, KK Smith, KK Smith, KK Smith, KK Smith, KS Thomson, KW Li, KW Tosney, L LeResche, L Olsson, L Ramage, LB Ruest, LS Gammill, LS Stone, LS Stone, M Bancroft, M Benjamin, M Bronner-Fraser, M Bronner-Fraser, M Hoso, M Jollie, M Jollie, M Jollie, M Jollie, M Linde-Medina, M Minoux, M Persson, M Qiu, M Qiu, M Sieber-Blum, M Simoes-Costa, M Takechi, M Tokita, M Tokita, MA Selleck, MA Shkoukani, MAJ Selleck, MJ Depew, MJ Depew, MJ Depew, MJ Depew, ML Martik, ML Moss, ML Moss, MM Dawson, MM Smith, MM Smith, MN Spyropoulos, MR Sanchez-Villagra, MR Sánchez-Villagra, MS Tyler, MSY Lee, N Anthwal, N Anthwal, N Anthwal, N Wang, NC Jones, NJ Giori, NM Young, NM Young, NN Soni, NS Bradley, O Campas, O Rieppel, OP Hamill, P Betancur, P Danaisawadi, P Hunt, P Kissel, P Kulesa, P Murray, P Murray, P Thorogood, P Wu, P Wu, PA Trainor, PA Trainor, PA Trainor, PA Trainor, PA Trainor, PA Trainor, PA Trainor, PD Henion, PDF Murray, PH Francis-West, PS Verma, PY Lwigale, R Cerny, R Derynck, R Diogo, R Luo, R Mallarino, R McBeath, R McLennan, R McLennan, R Owen, R Owen, R Presley, R Presley, R Sambasivan, R Sambasivan, R Schweitzer, RA Schneider, RA Schneider, RA Schneider, RA Schneider, RA Schneider, RA Schneider, RA Schneider, RA Schneider, RA Schneider, RA Yuodelis, RC Garcez, RC Mootoosamy, RC Solem, RG Harrison, RG Northcutt, RG Northcutt, RJ Gorlin, RL Carroll, RL Zusi, RW Oppenheim, RW Oppenheim, RW Oppenheim, RW Shufeldt, S Alappat, S Amin, S Creuzet, S Dupont, S Ekanayake, S Hörstadius, S Kavumpurath, S Krispin, S Kuraku, S Kuratani, S Kuratani, S Kuratani, S Kuratani, S Kuratani, S Kuratani, S Kuratani, S Lamichhaney, S Lautenschlager, S Lautenschlager, S Murakami, S Shibata, S Tajbakhsh, S Thomopoulos, S Wadhwa, SC Ahlgren, SC Ahlgren, SH Lee, SH Reynolds, SJ Gould, SJ Mathew, SL Horowitz, SL Prescott, SL Washburn, SR Roberts, SW Herring, T Hems, T Hirasawa, T Kantomaa, T Maeda, T Mammoto, T Matsuoka, T Miyashita, T Rowe, T Sato, T Sauka-Spengler, T Sauka-Spengler, T Square, T Thomas, T Yoshida, TA Appel, TA Mitsiadis, TA Mitsiadis, TC Fitzgerald, TE Parsons, TG Boyd, TH Huxley, TH Huxley, TL Vincent, V Govindarajan, V Hamburger, V Hamburger, V Shone, VL Naples, W Maier, WA Beresford, WA Beresford, WE Reif, WF Van den Heuvel, WG Hall, WJ Moore, WJ Moore, WK Parker, WM McLeod, X Jiang, X Li, XL Tu, Y Hashimoto, Y Shigetani, Y Shigetani, Y Shwartz, Y Song, Y Sugimoto   +395 more
core   +1 more source

Protocol for microinjection of rapamycin into the zebrafish habenula

STAR Protocols
Summary: Mechanistic target of rapamycin complex 1 (mTorC1) activity plays a crucial role in brain development. Here, we present an approach for rapamycin microinjection into the habenula of larval zebrafish to achieve localized inhibition of the mTorC1 ...
Olga Doszyn, Tomasz Dulski, Justyna Zmorzynska   +2 more
doaj   +1 more source

Novel targets of miR-30, a microRNA required for biliary development [v1; ref status: indexed, http://f1000r.es/1so]

F1000Research, 2013
MicroRNAs have been found to play a profound role in embryonic and post-natal development through their regulation of processes such as cell proliferation, differentiation, and morphogenesis.
Claire L. Le Guen, Joshua R. Friedman, Nicholas J. Hand   +2 more
doaj   +1 more source

Comparative transcriptomic analysis of the different developmental stages of ovary in red swamp crayfish Procambarus clarkii

BMC Genomics, 2021
Background The red swamp crayfish Procambarus clarkii is a freshwater species that possesses high adaptability, environmental tolerance, and fecundity. P. clarkii is artificially farmed on a large scale in China.
Yizhi Zhong, Wenbin Zhao, Zhangsheng Tang, Liming Huang, Xiangxing Zhu, Xiang Liang, Aifen Yan, Zhifa Lu, Yanling Yu, Dongsheng Tang, Dapeng Wang, Zhuanling Lu   +11 more
doaj   +1 more source

Natural Kinds in Evolution and Systematics: Metaphysical and Epistemological Considerations [PDF]

, 2008
Despite the traditional focus on metaphysical issues in discussions of natural kinds in biology, epistemological considerations are at least as important.
Brigandt, Ingo
core   +1 more source

Integrated Analysis of Summary Statistics to Identify Pleiotropic Genes and Pathways for the Comorbidity of Schizophrenia and Cardiometabolic Disease

Frontiers in Psychiatry, 2020
Genome-wide association studies (GWAS) have identified abundant risk loci associated with schizophrenia (SCZ), cardiometabolic disease (CMD) including body mass index, coronary artery diseases, type 2 diabetes, low- and high-density lipoprotein, total ...
Hao Liu, Hao Liu, Hao Liu, Yang Sun, Yang Sun, Xinxin Zhang, Xinxin Zhang, Shiyang Li, Shiyang Li, Dong Hu, Dong Hu, Lei Xiao, Lei Xiao, Yanghui Chen, Yanghui Chen, Lin He, Dao Wen Wang, Dao Wen Wang   +17 more
doaj   +1 more source

Drosophila as a model system to study nonautonomous mechanisms affecting tumour growth and cell death [PDF]

, 2018
The study of cancer has represented a central focus in medical research for over a century. The great complexity and constant evolution of the pathology require the use of multiple research model systems and interdisciplinary approaches.
Cordero, Julia B., Hodgson, Joseph A., Parvy, Jean-Philippe   +2 more
core   +3 more sources

Computational modeling to elucidate molecular mechanisms of epigenetic memory

, 2015
How do mammalian cells that share the same genome exist in notably distinct phenotypes, exhibiting differences in morphology, gene expression patterns, and epigenetic chromatin statuses?
Alsing, Andrews, Ang, Angel, Arnold, Bannister, Barth, Beisel, Benecke, Bhattacharya, Binder, Black, Buscaino, Bushey, Canzio, Cowieson, David-Rus, Dayarian, Deal, Dodd, Fonseca, Freddolino, Gaffney, Grauffel, Greer, Grewal, Grigoryev, Hanna, Hathaway, Henikoff, Herranz, Hodges, Jacobs, Korolev, Korolev, Kouzarides, Ku, Kulaeva, Lin, Margreitter, Margueron, Mendenhall, Muller, Papp, Pasque, Peinado, Piana, Potoyan, Prohaska, Raghavan, Rohlf, Sanbonmatsu, Sanli, Schwab, Schwammle, Sedighi, So, Sontag, Steffen, Takahashi, Teif, Thon, Wocjan, Xu, Yang, Yuan, Zee, Zhang, Zhang   +68 more
core   +1 more source