Results 61 to 70 of about 1,093,837 (334)
Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation
FEBS Letters, EarlyView.Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley +1 more source
Genetics and developmental biology of cooperation [PDF]
Molecular Ecology, 2017 AbstractDespite essential progress towards understanding the evolution of cooperative behaviour, we still lack detailed knowledge about its underlying molecular mechanisms, genetic basis, evolutionary dynamics and ontogeny. An international workshop “Genetics and Development of Cooperation,” organized by the University of Bern (Switzerland), aimed at ...
Filipa Cunha-Saraiva +10 more
openaire +4 more sources
Protocol for isolation and ATAC-seq library construction of zebrafish red blood cells
STAR Protocols, 2022 Summary: Understanding chromatin dynamics in red blood cells (RBCs) is critical for exploring the differentiation process and homeostasis maintenance during erythropoiesis.
Yanyan Ding, Feng Liu
doaj
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
An optical coherence microscope for 3-dimensional imaging in developmental biology [PDF]
, 2000 An optical coherence microscope (OCM) has been designed and constructed to acquire 3-dimensional images of highly scattering biological tissue. Volume-rendering software is used to enhance 3-D visualization of the data sets. Lateral resolution of the OCM
Fernandez, Andrew D. +9 more
core +2 more sources
Developmental biology of lichens [PDF]
New Phytologist, 1993 SUMMARYLichen‐forming fungi are a large, taxonomically diverse group of nutritional specialists which acquire fixed carbon from a population of minute green algal or cyanobacterial cells. Mycobionts of foliose or fruticose lichens differ from the rest of the fungi by expressing morphologically and anatomically complex symbiotic phenotypes.
openaire +3 more sources
Resynthesizing Evolutionary and Developmental Biology [PDF]
Developmental Biology, 1996 A new and more robust evolutionary synthesis is emerging that attempts to explain macroevolution as well as microevolutionary events. This new synthesis emphasizes three morphological areas of biology that had been marginalized by the Modern Synthesis of genetics and evolution: embryology, macroevolution, and homology.
Gilbert, Scott F. +2 more
openaire +3 more sources
iScience, 2022 Summary: Activity-dependent calcium signals in developing muscle play a crucial role in neuromuscular junction (NMJ) formation. However, its downstream effectors and interactions with other regulators of pre- and postsynaptic differentiation are poorly ...
Mehmet Mahsum Kaplan +1 more
doaj
FEBS Letters, EarlyView.The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp +5 more
wiley +1 more source
Developmental Biology: Tension at the Border [PDF]
Current Biology, 2009 A combination of biophysical measurements and computer simulation shows that a localised increase in cell bond tension prevents cell mixing at the anterior-posterior compartment boundary of Drosophila wing imaginal discs.
Jean-Paul Vincent, David Irons
openaire +3 more sources