Results 61 to 70 of about 488,730 (215)
Developmental Biology: Tension at the Border [PDF]
A combination of biophysical measurements and computer simulation shows that a localised increase in cell bond tension prevents cell mixing at the anterior-posterior compartment boundary of Drosophila wing imaginal discs.
Jean-Paul Vincent, David Irons
openaire +3 more sources
Summary: The mitochondrial unfolded protein response (UPRmt) is an organellar stress signaling pathway that functions to detect and restore disruption of mitochondrial proteostasis.
Yi-Fan Lin, Jessica Sam, Todd Evans
doaj
Summary: Epithelia form protective permeability barriers that selectively allow the exchange of material while maintaining tissue integrity under extreme mechanical, chemical, and bacterial loads. Here, we report in the Drosophila follicular epithelium a
Sarayu Row, Yi-Chun Huang, Wu-Min Deng
doaj
Cancer Networks: A general theoretical and computational framework for understanding cancer [PDF]
We present a general computational theory of cancer and its developmental dynamics. The theory is based on a theory of the architecture and function of developmental control networks which guide the formation of multicellular organisms. Cancer networks are special cases of developmental control networks.
arxiv
Horizontal mtDNA transfer between cells is common during mouse development
Summary: Cells transmit their genomes vertically to daughter cells during cell divisions. Here, we demonstrate the occurrence and extent of horizontal mitochondrial (mt)DNA acquisition between cells that are not in a parent-offspring relationship ...
Nuria Marti Gutierrez+15 more
doaj
Robust and Irreversible Development in Cell Society as a General Consequence of Intra-Inter Dynamics [PDF]
A dynamical systems scenario for developmental cell biology is proposed, based on numerical studies of a system with interacting units with internal dynamics and reproduction. Diversification, formation of discrete and recursive types, and rules for differentiation are found as a natural consequence of such a system.
arxiv +1 more source
Medulloblastoma: A problem of developmental biology [PDF]
The identification of SUFU mutations in desmoplastic medulloblastoma provides new insights into vertebrate Hedgehog signaling and brain tumor formation.
Joshua B. Rubin, David H. Rowitch
openaire +3 more sources
A newly emerged seedling, given light and water, but no external source of minerals, uses its internal mineral nutrient reserves effectively for an early establishment.
T. Mandizvo, A.O. Odindo
doaj
Summary: A conceptual framework for understanding abnormal endometrial decidualization, with considerable significance for the diagnosis and treatment of abnormal decidualization-related changes in non-receptive endometrium in implantation failure during
Aixia Liu+7 more
doaj
Non-equilibrium statistical physics, transitory epigenetic landscapes, and cell fate decision dynamics [PDF]
Statistical physics provides a useful perspective for the analysis of many complex systems; it allows us to relate microscopic fluctuations to macroscopic observations. Developmental biology, but also cell biology more generally, are examples where apparently robust behaviour emerges from highly complex and stochastic sub-cellular processes.
arxiv