Results 61 to 70 of about 1,157,389 (344)

Sirt1 promotes tissue regeneration in zebrafish through regulating the mitochondrial unfolded protein response

open access: yesiScience, 2021
Summary: The mitochondrial unfolded protein response (UPRmt) is an organellar stress signaling pathway that functions to detect and restore disruption of mitochondrial proteostasis.
Yi-Fan Lin, Jessica Sam, Todd Evans
doaj   +1 more source

Introduction [PDF]

open access: yes, 1999
This volume of twelve specially commissioned essays about species draws on the perspectives of prominent researchers from anthropology , botany, developmental psychology , the philosophy of biology and science, protozoology, and zoology .
Wilson, Robert A.
core  

Homeostasis as the Mechanism of Evolution. [PDF]

open access: yes, 2015
Homeostasis is conventionally thought of merely as a synchronic (same time) servo-mechanism that maintains the status quo for organismal physiology. However, when seen from the perspective of developmental physiology, homeostasis is a robust, dynamic ...
Torday, John S
core   +2 more sources

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

The Machine Conception of the Organism in Development and Evolution: A Critical Analysis [PDF]

open access: yes, 2014
This article critically examines one of the most prevalent metaphors in modern biology, namely the machine conception of the organism (MCO). Although the fundamental differences between organisms and machines make the MCO an inadequate metaphor for ...
Nicholson, Daniel J.
core  

Developmental imaging genetics: challenges and promises for translational research [PDF]

open access: yes, 2006
Advances in molecular biology, neuroimaging, genetic epidemiology, and developmental psychopathology have provided a unique opportunity to explore the interplay of genes, brain, and behavior within a translational research framework.
Hariri, A.R.   +2 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Drosophila SPARC collagen IV chaperone-like activity essential for development is unique to the fat body

open access: yesiScience
Summary: Drosophila fat body-derived SPARC acts as a chaperone for collagen IV (Col(IV)), enabling their diffusion and incorporation into distal tissue basement membranes (BMs). Disruption of SPARC or Col(IV) production by the fat body is lethal, despite
Samuel Delage   +4 more
doaj   +1 more source

Mathematical models in Developmental Biology [PDF]

open access: yes, 2016
We will introduce some of the mathematical modeling tools that have been introduced in the field of Developmental Biology, focusing in specific problems in embryogenesis.
Calvo Yagüe, Juan
core  

Genes Classical And Genes Developmental: The Different Uses Of The Gene In Evolutionary Synthesis [PDF]

open access: yes, 2000
Dobzhansky (1964) stated that “Nothing in biology makes sense except in the light of evolution,” and the function of the gene is no exception. The use of genes in population genetics and developmental genetics differs significantly.
Gilbert, Scott F.
core   +3 more sources

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