Results 61 to 70 of about 1,092,027 (335)
Developmental Biology Is “Cruzing” [PDF]
AbstractThe 2004 Santa Cruz Developmental Biology Meeting took place August 5th–8th and covered a diverse range of current topics in developmental biology. This report discusses some of the highlights.
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Genetics and developmental biology of cooperation [PDF]
AbstractDespite essential progress towards understanding the evolution of cooperative behaviour, we still lack detailed knowledge about its underlying molecular mechanisms, genetic basis, evolutionary dynamics and ontogeny. An international workshop “Genetics and Development of Cooperation,” organized by the University of Bern (Switzerland), aimed at ...
Filipa Cunha-Saraiva+10 more
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Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Summary: Activity-dependent calcium signals in developing muscle play a crucial role in neuromuscular junction (NMJ) formation. However, its downstream effectors and interactions with other regulators of pre- and postsynaptic differentiation are poorly ...
Mehmet Mahsum Kaplan+1 more
doaj
Resynthesizing Evolutionary and Developmental Biology [PDF]
A new and more robust evolutionary synthesis is emerging that attempts to explain macroevolution as well as microevolutionary events. This new synthesis emphasizes three morphological areas of biology that had been marginalized by the Modern Synthesis of genetics and evolution: embryology, macroevolution, and homology.
Gilbert, Scott F.+2 more
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Through the dark continent: African trypanosome development in the tsetse fly [PDF]
African trypanosomes are unicellular flagellated parasites causing trypanosomiases in Africa, a group of severe diseases also known as sleeping sickness in human and nagana in cattle.
Rotureau, Brice, Van Den Abbeele, Jan
core +4 more sources
Making tau amyloid models in vitro: a crucial and underestimated challenge
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Sox9 regulates melanocytic fate decision of adult hair follicle stem cells
Summary: The bulge of hair follicles harbors Nestin+ (neural crest like) stem cells, which exhibit the potential to generate various cell types including melanocytes.
Isabel Stüfchen+6 more
doaj
Developmental biology of lichens [PDF]
SUMMARYLichen‐forming fungi are a large, taxonomically diverse group of nutritional specialists which acquire fixed carbon from a population of minute green algal or cyanobacterial cells. Mycobionts of foliose or fruticose lichens differ from the rest of the fungi by expressing morphologically and anatomically complex symbiotic phenotypes.
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Developmental Biology: Tension at the Border [PDF]
A combination of biophysical measurements and computer simulation shows that a localised increase in cell bond tension prevents cell mixing at the anterior-posterior compartment boundary of Drosophila wing imaginal discs.
Jean-Paul Vincent, David Irons
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