Results 71 to 80 of about 608,296 (310)

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

open access: yesFEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali   +3 more
wiley   +1 more source

The Generation Of Novelty: The Province Of Developmental Biology [PDF]

open access: yes, 2006
A response to Michael Ruse\u27s Forty Years A Philosopher Of Biology: Why EvoDevo Makes Me Still Excited About My Subject
Gilbert, Scott F.
core   +2 more sources

Developmental Biology Is “Cruzing” [PDF]

open access: yesDevelopmental Cell, 2004
AbstractThe 2004 Santa Cruz Developmental Biology Meeting took place August 5th–8th and covered a diverse range of current topics in developmental biology. This report discusses some of the highlights.
openaire   +2 more sources

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

Protocol for isolation and ATAC-seq library construction of zebrafish red blood cells

open access: yesSTAR Protocols, 2022
Summary: Understanding chromatin dynamics in red blood cells (RBCs) is critical for exploring the differentiation process and homeostasis maintenance during erythropoiesis.
Yanyan Ding, Feng Liu
doaj  

Nothing makes sense in deep learning, except in the light of evolution [PDF]

open access: yesarXiv, 2022
Deep Learning (DL) is a surprisingly successful branch of machine learning. The success of DL is usually explained by focusing analysis on a particular recent algorithm and its traits. Instead, we propose that an explanation of the success of DL must look at the population of all algorithms in the field and how they have evolved over time.
arxiv  

Mathematical models in Developmental Biology [PDF]

open access: yes, 2016
We will introduce some of the mathematical modeling tools that have been introduced in the field of Developmental Biology, focusing in specific problems in embryogenesis.
Calvo Yagüe, Juan
core  

An interview with Michael Barresi [PDF]

open access: yes, 2021
Michael Barresi is Professor of Biological Sciences at Smith College, Northampton, MA, USA, where he uses the zebrafish to understand central nervous system development.
Barresi, Michael J.F., Eve, Alex
core   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Counteractive and cooperative actions of muscle β-catenin and CaV1.1 during early neuromuscular synapse formation

open access: yesiScience, 2022
Summary: Activity-dependent calcium signals in developing muscle play a crucial role in neuromuscular junction (NMJ) formation. However, its downstream effectors and interactions with other regulators of pre- and postsynaptic differentiation are poorly ...
Mehmet Mahsum Kaplan   +1 more
doaj  

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