Results 91 to 100 of about 580,764 (305)

Inhibition of late endosomal maturation restores Wnt secretion in Caenorhabditis elegans vps-29 retromer mutants.

, 2014
Secretion of Wnt proteins is mediated by the Wnt sorting receptor Wls, which transports Wnt from the Golgi to the cell surface for release. To maintain efficient Wnt secretion, Wls is recycled back to the trans-Golgi network (TGN) through a retromer ...
Sub Developmental Biology, Korswagen, Hendrik, de Groot, R., Harterink, M., Lorenowicz, M.J., Macurkova, M., Developmental Biology   +6 more
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Protamine sequence determines species-specific nuclear shape and histone retention

iScience
Summary: The nuclear shape observed after the forced expression of mouse or human protamine 1 (PRM1) in fibroblasts led us to propose the hypothesis that the PRM1 sequence plays an important role in imposing the overall shape of the protaminized nucleus.
Marta Czernik, Luca Palazzese, Dawid Winiarczyk, Domenico Iuso, Saadi Khochbin, Josef Fulka, Helena Fulka, Rocío Villafranca, Juan Antonio Rielo, Ana Sanchez-Rodriguez, Nerea Latorre, Clara Agudo-Rios, Eduardo R.S. Roldan, Maria Eugenia Teves, Pasqualino Loi   +14 more
doaj   +1 more source

The Nurture of Nature: Biology, Psychology and Culture [PDF]

, 2010
In this thesis I explore what consequences taking development seriously in evolutionary considerations will have for how we understand the evolution of psychology and culture.
Hannon, Elizabeth Mary, HANNON, ELIZABETH,MARY   +1 more
core  

Pluripotency in the light of the developmental hourglass [PDF]

, 2014
The hourglass model of development postulates divergence in early and late embryo development bridged by a period of developmental constraint at mid-embryogenesis.
Sub Developmental Biology, Kuijk, Ewart, Cuppen, Edwin, Onderzoek, Geijsen, Niels, Regenerative Medicine, Stem Cells & Cancer, CSCA TR1   +6 more
core   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Embryonic lineage-specific iPSC-derived mesenchymal stem/stromal cells exhibit different morphologies and intrinsic functions

iScience
Summary: Mesenchymal stem/stromal cells (MSCs) have great potential in regenerative medicine owing to their multilineage differentiation capacity. However, tissue-derived MSCs (tMSCs) exhibit inconsistent characteristics.
Linh Nguyen, Souta Motoike, Denise Zujur, Keiko Yoshizawa, Yasuhiro Takashima, Akiyoshi Uezumi, Kazuhiro Furuhashi, Shoichi Maruyama, Yonghui Jin, Junya Toguchida, Hidetoshi Sakurai, Makoto Ikeya   +11 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Estrogen-induced inhibition of spermatogenesis in zebrafish is largely reversed by androgen [PDF]

, 2018
The hormonal regulation of spermatogenesis involves both gonadotropins and steroid hormones. Long-term in vivo exposure of adult zebrafish to estrogen impaired spermatogenesis associated with an androgen insufficiency, possibly induced by inhibiting ...
de Castro Assis, Luiz Henrique, Gómez-González, Nuria Esther, Sub Developmental Biology, de Nóbrega, Rafael Henrique, Bogerd, Jan, Schulz, Rüdiger Winfried, Developmental Biology   +6 more
core   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source