Results 91 to 100 of about 7,143,981 (292)
Autophagy: A Forty-Year Search for a Missing Membrane Source [PDF]
, 2006 Autophagy is the major self-degradative process in eukaryotic cells, with fundamental roles in cellular and organismal homeostasis, and is involved in many developmental and pathological situations.
Juhasz Gabor +5 more
core +2 more sources
F1000Research, 2015 Recently, the Mouse ENCODE Consortium reported that comparative gene expression data from human and mouse tend to cluster more by species rather than by tissue.
Yoav Gilad, Orna Mizrahi-Man
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Supported employment services for individuals experiencing intellectual and developmental disabilities (I/DD) [PDF]
, 2016 This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from PDF caption (viewed on July 6, 2016)."The Office ...
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Frontiers in Cell and Developmental BiologyDEAD-box RNA helicase Vasa is required for gonad development and fertility in multiple animals. Vasa is implicated in many crucial aspects of Drosophila oogenesis, including translation regulation, primordial germ cell specification, piRNA silencing of ...
Vladimir E. Adashev +6 more
doaj +1 more source
Amphioxus molecular biology: insights into vertebrate evolution and developmental mechanisms
Canadian Journal of Zoology, 2005 The cephalochordate amphioxus is the best available proxy for the last common invertebrate ancestor of the vertebrates. During the last decade, the developmental genetics of amphioxus have been extensively examined for insights into the evolutionary origin and early evolution of the vertebrates.
Shimeld, S, Holland, N
openaire +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Texas Council for Developmental Disabilities Annual Report [PDF]
, 1999 Report for the expenditures and projects pursued by the Texas Planing for Developmental Disabilities during the fiscal ...
Texas Council for Developmental Disabilities
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Molecular mechanisms of Tay Sachs Disease: calcium, excitotoxicity, and apoptosis [PDF]
, 2007 The objective is to investigate the molecular mechanisms leading to neurodegeneration in Tay Sachs disease, a lysosomal storage disorder caused by a deficiency in the enzyme hexosaminidase A.
King, John-Paul
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