Results 101 to 110 of about 7,143,981 (292)

Molecular marker of memory formation reveals complex mechanisms of developmental learning

BMC Neuroscience
The intersection of age- and experience-dependent processes influence learning throughout development, and developmental learning can have long-term effects on behavior.
Rebecca M. Butler, Konstance D. Delis, Kruthika V. Maheshwar, Karelys D. Montañez, Selin Yalcindag, Sarah E. London   +5 more
doaj   +1 more source

The impact of Di(2-ethylhexyl) phthalate on human organ development: mechanisms and clinical relevance review

Frontiers in Public Health
Di(2-ethylhexyl) phthalate (DEHP) is a commonly used plasticizer that has raised significant concerns due to its strong endocrine-disrupting effects, which are closely associated with developmental toxicity.
Xiduo Zhao, Xiduo Zhao, Lianyu Hua, Lianyu Hua, Youjun Xiong, Youjun Xiong, Fuyou Shi, Fuyou Shi, Yilin Zhong, Yilin Zhong, Shangwei Zhang, Dongmin Yu, Chengnan Tian   +12 more
doaj   +1 more source

Drosophila Model for the Analysis of Genesis of LIM-kinase 1-Dependent Williams-Beuren Syndrome Cognitive Phenotypes: INDELs, Transposable Elements of the Tc1/Mariner Superfamily and MicroRNAs

Frontiers in Genetics, 2017
Genomic disorders, the syndromes with multiple manifestations, may occur sporadically due to unequal recombination in chromosomal regions with specific architecture.
Elena V. Savvateeva-Popova, Aleksandr V. Zhuravlev, Václav Brázda, Gennady A. Zakharov, Alena N. Kaminskaya, Anna V. Medvedeva, Ekaterina A. Nikitina, Ekaterina A. Nikitina, Elena V. Tokmatcheva, Julia F. Dolgaya, Dina A. Kulikova, Olga G. Zatsepina, Sergei Y. Funikov, Sergei S. Ryazansky, Michail B. Evgen‘ev   +14 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

The Spetses Summer Schools on Molecular and Developmental Biology [PDF]

, 2013
The Spetses Summer Schools - A Tribute to Marianne Grunberg-Manago - Founding and More than 40 Years of the School - How Spetses Summer Schools Were Run - Financing the Spetses Summer Schools - Past and Future of the Spetses Summer Schools - List
Feldmann, Horst
core   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Harmony in the Molecular Orchestra of Hearing: Developmental Mechanisms from the Ear to the Brain

Annual Review of Neuroscience
Auditory processing in mammals begins in the peripheral inner ear and extends to the auditory cortex. Sound is transduced from mechanical stimuli into electrochemical signals of hair cells, which relay auditory information via the primary auditory neurons to cochlear nuclei. Information is subsequently processed in the superior olivary complex, lateral
Pyott, S. J., Pavlínková, G. (Gabriela), Yamoah, E. N., Fritzsch, B.   +3 more
openaire   +3 more sources

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

State plan for Developmental Disabilities

, 2008
Title from PDF p. [1] (viewed on Oct. 16, 2008).; Received as an e-mail attachment.; "Created: 10/1/2008 ..."--Document properties screen."This 'Supplemental Information' is the reader-friendly version of the 2006 Update to the 2007-2011 State Plan.
Ohio Developmental Disabilities Council.
core