Results 101 to 110 of about 823,004 (286)
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Evolutionary Conservation of Organ Development between Drosophila and Mammals
Shiyan dongwu yu bijiao yixueDrosophila， as a classic model organism， exhibits high evolutionary conservation with mammals in molecular regulatory networks， signal pathway transduction， and cell fate determination mechanisms involved in its organ development.
GAO Yinghao, WU Wei
doaj +1 more source
F1000Research, 2014 One of the most striking patterns in comparative biology is the negative correlation between lifespan and fecundity observed in comparisons among species.
Yingxue Ren, Kimberly A. Hughes
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
"Life" shaped by genes that depend on their surrounds [PDF]
, 2011 Never was dogmatic reductionism helpful in conceiving the phenomenon of life. The post-genomic era has made it clear that genes alone cannot explain the functioning of whole organisms.
Layer, Paul Gottlob
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FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Functional characterization of hexokinases in the moss Physcomitrella patens [PDF]
, 2005 Carbohydrates are important nutrients and structural components in all living organisms. In plants they affect the developmental and metabolic processes throughout the plant life cycle.
Olsson, Tina
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AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Frontiers in Public HealthDi(2-ethylhexyl) phthalate (DEHP) is a commonly used plasticizer that has raised significant concerns due to its strong endocrine-disrupting effects, which are closely associated with developmental toxicity.
Xiduo Zhao +12 more
doaj +1 more source
Session 5: Development, Neuroscience and Evolutionary Psychology [PDF]
, 2002 Proceedings of the Pittsburgh Workshop in History and Philosophy of Biology, Center for Philosophy of Science, University of Pittsburgh, March 23-24 2001 Session 5: Development, Neuroscience and Evolutionary ...
Machamer, Peter +3 more
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