Results 121 to 130 of about 163,366 (294)
A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling +16 more
wiley +1 more source
Maximizing the potential of EEG as a developmental neuroscience tool. [PDF]
Dev Cogn Neurosci, 2023 Buzzell GA +4 more
europepmc +1 more source
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants
Annals of Clinical and Translational Neurology, EarlyView.Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold +12 more
wiley +1 more source
Editorial: Advanced analytic techniques in developmental neuroscience. [PDF]
Front Neurosci, 2022 Levman J, Takahashi E.
europepmc +1 more source
Developmental cognitive neuroscience
Higher Brain Function Research, 2004 発達認知神経科学とは，脳の成長と心的プロセスの発達の関係を探る学問である。神経心理学の場合，発達という変化に注目して認知機能の異常を調べるという側面からこの分野にかかわっているが，モジュールの生得性を前提としている。Williams症候群は第7染色体11.23領域の半接合体欠失による隣接遺伝子症候群であり，神経心理学的には言語が良好で視空間認知は不良という解離のみられるのが特徴で，特定の遺伝子がこの認知パターン形成にかかわると考えられ研究されている。しかし近年の研究からは，単純な「解離」ではなく，また単一の遺伝子が特定の認知機能と直接には結びつかないことも示されている。モジュールの考え方には生得主義以外にも構成主義や神経構成主義があり，その立場によって得られたデータの解釈も異なってくる ...
openaire +2 more sources
Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi +8 more
wiley +1 more source
Leveraging the developmental neuroscience of caregiving to promote resilience among youth exposed to adversity. [PDF]
Dev Psychopathol, 2023 Gee DG, Cohodes EM.
europepmc +1 more source
SPG4 and Dementia: Expanding the Clinical Spectrum
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source
In this chapter, the authors propose neural reuse as a promising unifying framework for the advance of developmental cognitive neuroscience. In order to do so, first, the authors describe the hypothesis of neural reuse and some of the evidence for its ...
Penner, Marcie +3 more
core +2 more sources