Results 271 to 280 of about 1,316,154 (307)

Long‐Term Memory Updating Parallels Altered Awake and Sleep Hippocampal Replays

open access: yesAdvanced Science, EarlyView.
This study introduces a behavioral paradigm for memory updating and reveals underlying hippocampal mechanisms. Replays of place cells predict future behavioral choices during behavior and show a bias toward high‐reward locations during non‐rapid eye movement (NREM) sleep, specifically within the memory updating process.
Jifu Tong   +14 more
wiley   +1 more source

Mechanobiological Dynamics‐Inspired Mechanomodulatory Biomaterials

open access: yesAdvanced Science, EarlyView.
Recent advances in biomaterial‐mediated mechanomodulation of stem cell fate, encompassing 2, 3, and 4D systems and their synergy with artificial intelligence is overviewed. By integrating knowledge from diverse fields, this review ultimately aims to inspire the design of smarter biomaterial systems that can accelerate the clinical translation of ...
Letao Yang   +6 more
wiley   +1 more source

Genome‐Wide by Lifetime Environment Interaction Studies of Brain Imaging Phenotypes

open access: yesAdvanced Science, EarlyView.
This study explores genome‐wide by lifetime environment interactions on brain imaging phenotypes. Gene‐environment interactions explain more phenotypic variance than main effects, pinpoint regulatory variants, and reveal exposure‐specific biological pathways.
Sijia Wang   +51 more
wiley   +1 more source

Correction: TOPSS: TOlerability of transcranial direct current stimulation in Pediatric Stroke Survivors. [PDF]

open access: yesFront Hum Neurosci
Fraser S   +6 more
europepmc   +1 more source

Interactions of Interaural Time and Level Differences in Spatial Hearing with Cochlear Implants

open access: yesAdvanced Science, EarlyView.
Differences in timing (ΔT) are weighted heavily compared to differences in loudness (ΔL) in binaural hearing with cochlear implants. Abstract Normally hearing humans can localize sound sources quite accurately, with minimum audible angles as small as 1°. To achieve this, these auditory pathways combine information from multiple acoustic cues, including
Sarah Buchholz   +3 more
wiley   +1 more source

Predicting Immunotherapy Outcomes in NSCLC Using RNA and Pathology from Multicenter Clinical Trials

open access: yesAdvanced Science, EarlyView.
LIRA, a machine learning‐based model, is developed using transcriptomic data from 891 NSCLC patients in the OAK and POPLAR cohorts. Its predictive performance is validated in multiple external cohorts. Patients stratified by LIRA‐score exhibit distinct clinical characteristics and tumor microenvironment profiles.
Zhaojun Wang   +32 more
wiley   +1 more source

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