Long‐Term Memory Updating Parallels Altered Awake and Sleep Hippocampal Replays
This study introduces a behavioral paradigm for memory updating and reveals underlying hippocampal mechanisms. Replays of place cells predict future behavioral choices during behavior and show a bias toward high‐reward locations during non‐rapid eye movement (NREM) sleep, specifically within the memory updating process.
Jifu Tong +14 more
wiley +1 more source
Mechanobiological Dynamics‐Inspired Mechanomodulatory Biomaterials
Recent advances in biomaterial‐mediated mechanomodulation of stem cell fate, encompassing 2, 3, and 4D systems and their synergy with artificial intelligence is overviewed. By integrating knowledge from diverse fields, this review ultimately aims to inspire the design of smarter biomaterial systems that can accelerate the clinical translation of ...
Letao Yang +6 more
wiley +1 more source
Editorial: Neuromuscular and kinematic dynamics in human movement adaptation. [PDF]
Singh RE, Davies JL, Purcell C.
europepmc +1 more source
Genome‐Wide by Lifetime Environment Interaction Studies of Brain Imaging Phenotypes
This study explores genome‐wide by lifetime environment interactions on brain imaging phenotypes. Gene‐environment interactions explain more phenotypic variance than main effects, pinpoint regulatory variants, and reveal exposure‐specific biological pathways.
Sijia Wang +51 more
wiley +1 more source
Correction: TOPSS: TOlerability of transcranial direct current stimulation in Pediatric Stroke Survivors. [PDF]
Fraser S +6 more
europepmc +1 more source
Interactions of Interaural Time and Level Differences in Spatial Hearing with Cochlear Implants
Differences in timing (ΔT) are weighted heavily compared to differences in loudness (ΔL) in binaural hearing with cochlear implants. Abstract Normally hearing humans can localize sound sources quite accurately, with minimum audible angles as small as 1°. To achieve this, these auditory pathways combine information from multiple acoustic cues, including
Sarah Buchholz +3 more
wiley +1 more source
Editorial: Advancing neurodevelopmental disorder models with human iPSC and multi-omics integration. [PDF]
Afshar-Saber W, Metodieva V, D'Amore A.
europepmc +1 more source
Predicting Immunotherapy Outcomes in NSCLC Using RNA and Pathology from Multicenter Clinical Trials
LIRA, a machine learning‐based model, is developed using transcriptomic data from 891 NSCLC patients in the OAK and POPLAR cohorts. Its predictive performance is validated in multiple external cohorts. Patients stratified by LIRA‐score exhibit distinct clinical characteristics and tumor microenvironment profiles.
Zhaojun Wang +32 more
wiley +1 more source
Editorial: Motivation seen through the kaleidoscope of multi-disciplinarity and multi-scales: towards the emergence of new paradigms and perspectives favored by crossed looks. [PDF]
Terrier B, Bittencourt JC, Parrot S.
europepmc +1 more source

