Results 81 to 90 of about 181,058 (246)

Brain Plasticity and Motor Practice in Cognitive Aging

open access: yesFrontiers in Aging Neuroscience, 2014
For more than two decades, there have been extensive studies of experience-based neural plasticity exploring effective applications of brain plasticity for cognitive and motor development.
Liuyang eCai   +4 more
doaj   +1 more source

THE ART OF WAR: PATTERNS AND MECHANISMS UNDERLYING PREDATOR-INDUCED PLASTICITY OF AMPHIBIANS [PDF]

open access: yes, 2013
Organisms often employ phenotypic plasticity as a strategy to cope with variable environments. This is particularly true of predation threats, wherein prey induce defenses to reduce detection or capture by predators.
Relyea, Rick A, Shaffery, Heather M
core  

Prenatal stress and enhanced developmental plasticity [PDF]

open access: yesJournal of Neural Transmission, 2018
Two separate lines of inquiry indicate (a) that prenatal stress is associated with heightened behavioral and physiological reactivity, and (b) that these postnatal phenotypes are associated with increased susceptibility to both positive and negative developmental experiences and environmental exposures.
Hartman, Sarah, Belsky, Jay
openaire   +4 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

The evolution and comparative neurobiology of endocannabinoid signalling [PDF]

open access: yes, 2012
CB(1)- and CB(2)-type cannabinoid receptors mediate effects of the endocannabinoids 2-arachidonoylglycerol (2-AG) and anandamide in mammals. In canonical endocannabinoid-mediated synaptic plasticity, 2-AG is generated postsynaptically by diacylglycerol ...
Devane W. A.   +4 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Cross-Generational Effects and Non-random Developmental Response to Temperature Variation in Paramecium

open access: yesFrontiers in Cell and Developmental Biology, 2020
Unicellular organisms such as ciliates are largely neglected in research on adaptive developmental plasticity, although their nuclear dualism offers ideal circumstances to study development outside an embryonic context.
Rebecca Hagen   +2 more
doaj   +1 more source

Ageing, plasticity, and cognitive reserve in connectionist networks [PDF]

open access: yes, 2008
Neurocomputational modeling has suggested that a range of mechanisms can lead to reductions in functional plasticity across development (Thomas & Johnson, 2006).
Thomas, Michael S.C.
core   +1 more source

Strengths and weakness of neuroscientific investigations of childhood poverty: Future directions [PDF]

open access: yes, 2015
The neuroscientific study of child poverty is a topic that has only recently emerged. In comparison with previous reviews (e.g., Hackman and Farah, 2009; Lipina and Colombo, 2009; Hackman et al., 2010; Raizada and Kishiyama, 2010; Lipina and Posner, 2012)
Lipina, Sebastián Javier   +1 more
core   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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