Results 101 to 110 of about 894,049 (295)

Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization

open access: yesAdvanced Science, EarlyView.
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin   +11 more
wiley   +1 more source

Sources of Unreliable Testimony from Children [PDF]

open access: yes, 2014
We distilled research findings on sources of unreliable testimony from children into four principles that capture how the field of forensic developmental psychology conceptualizes this topic.
Brubacher, Sonja P.   +2 more
core   +1 more source

Machine‐Learning Decomposition Identifies a Big Two Structure in Human Personality with Distinct Neurocognitive Profiles

open access: yesAdvanced Science, EarlyView.
Using machine learning on a mega‐scale global dataset (n = 1,336,840) reveals a robust personality trait architecture beyond the Big Five. A Big Two model, broadly capturing social engagement and internal mentation, defines a geometric space that links personality to neurocognitive profiles.
Kaixiang Zhuang   +7 more
wiley   +1 more source

Problematic Alcohol Use and Problem Gambling: Associations to Structural and Functional aspects of Social Ties in a Finnish Population Sample

open access: yesNordic Studies on Alcohol and Drugs, 2016
AIMS – This study aims to explore associations between structural and functional aspects of social networks and relationships (here labelled social ties) among individuals exhibiting problematic alcohol use and problem gambling, respectively.
Nordmyr Johanna   +2 more
doaj   +1 more source

Using Lower-Division Developmental Education Students as Teaching Assistants [PDF]

open access: yes, 2002
There has been little research on the experiences of undergraduate teaching assistants, and this small body of information is usually tightly focused on traditional disciplinary concerns like sociology, psychology, and communications.
Jacobs, Walter R
core   +1 more source

A Tac1‐Expressing Brainstem Pathway Underlies the Pathogenesis of Trigeminal Neuralgia

open access: yesAdvanced Science, EarlyView.
A critical TG‐Sp5CTac1‐PBNTac1 pathway drives trigeminal neuropathic pain (TNP). Tac1‐expressing parabrachial nucleus (PBNTac1) neurons exhibit heightened responses to innocuous stimuli in TNP, and chemogenetic inhibition of these neurons effectively prevents TNP development.
Liting Sun   +11 more
wiley   +1 more source

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