Results 141 to 150 of about 357,386 (324)
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Tracing blastomere fate choices of early embryos in single cell culture [PDF]
, 2010 Blastomeres of early vertebrate embryos undergo numerous fate choices for division, motility, pluripotency maintenance and restriction culminating in various cell lineages.
Chang Ming Li +11 more
core +1 more source
The Nuclear Actin-Related Protein ARP6 Is a Pleiotropic Developmental Regulator Required for the Maintenance ofFLOWERING LOCUS CExpression and Repression of Flowering inArabidopsis w [PDF]
, 2005 Roger B. Deal +3 more
openalex +1 more source
Genome-wide analysis of lncRNAs points to their roles in the modulation of developmental regulator expression during plant male germline development [PDF]
, 2022 Neeta Lohani +4 more
openalex +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Medical SciencesCalcium/calmodulin-dependent protein kinase II (CaMKII) comprises multiple isoforms with distinct nuclear variants that exert transcriptional control in a context-dependent manner.
Areli Marlene Gaytán-Gómez +16 more
doaj +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Developmental Expression of NCS-1 (Frequenin), a Regulator of Kv4 K+ Channels, in Mouse Heart [PDF]
, 2003 Tomoe Y. Nakamura +5 more
openalex +1 more source
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
npj Biological Timing and SleepCircadian rhythms align biological processes with environmental cycles to enhance fitness. Eukaryotic circadian oscillators rely on transcriptional–translational feedback loops, although specific oscillator components vary among lineages.
Roderick W. Kumimoto +3 more
doaj +1 more source