Results 191 to 200 of about 334,033 (329)

ALOG domains: provenance of plant homeotic and developmental regulators from the DNA-binding domain of a novel class of DIRS1-type retroposons [PDF]

, 2012
Lakshminarayan M. Iyer, L. Aravind
openalex   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source

In planta genome editing in citrus facilitated by co-expression of CRISPR/Cas and developmental regulators. [PDF]

Plant J
Kelly G, Plesser E, Bdolach E, Arroyave M, Belausov E, Doron-Faigenboim A, Rozen A, Zemach H, Zach YY, Goldenberg L, Arad T, Yaniv Y, Sade N, Sherman A, Eyal Y, Carmi N.   +15 more
europepmc   +1 more source

Developmentally Regulated Novel Non-coding Anti-sense Regulators of mRNA Translation in Trypanosoma brucei [PDF]

, 2020
K. Shanmugha Rajan, Tirza Doniger, Smadar Cohen‐Chalamish, Praveenkumar Rengaraj, Beathrice Galili, Saurav Aryal, Ron Unger, Christian Tschudi, Shulamit Michaeli   +8 more
openalex   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

Molecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed, Lucas Mani, Muhammad Bilal Mirza, Ashtyn McAdoo, Takahito Kondo, Hidenori Tanaka, Nicole Meeks, Eben Rosenthal, Marisa Hom   +8 more
wiley   +1 more source

Developmental regulators in promoting genetic transformation efficiency in maize and other plants

Current Plant Biology
Given global agricultural challenges such as population growth, climate change, and limitations on resources and the environment, as well as increasing diversity in breeding goals, relying on traditional breeding methods is inadequate to provide food ...
Yilin Jiang, Xun Wei, Meirui Zhu, Xiaoyan Zhang, Qingping Jiang, ZiXiao Wang, Yanyong Cao, Xueli An, Xiangyuan Wan   +8 more
doaj  

Root hair developmental regulators orchestrate drought triggered microbiome changes and the interaction with beneficial Rhizobiaceae. [PDF]

Nat Commun
Wang Z, Li Z, Zhang Y, Liao J, Guan K, Zhai J, Meng P, Tang X, Dong T, Song Y.   +9 more
europepmc   +1 more source

Flower heads in Asteraceae-recruitment of conserved developmental regulators to control the flower-like inflorescence architecture. [PDF]

Hortic Res, 2018
Elomaa P, Zhao Y, Zhang T.
europepmc   +1 more source

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

Molecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho, Yubin Hah, Eunsik Yun, Hye In Ka, Aram Lee, Sora Han, Dawn Lee, Sung Wook Kim, Jong Hoon Park, Byung Su Kwon, Young Yang, Jongmin Kim   +11 more
wiley   +1 more source