Bradysia (Sciara) coprophila larvae up-regulate DNA repair pathways and down-regulate developmental regulators in response to ionizing radiation. [PDF]
Urban JM+8 more
europepmc +1 more source
Altered expression of developmental regulators of parvalbumin and somatostatin neurons in the prefrontal cortex in schizophrenia. [PDF]
Volk DW, Edelson JR, Lewis DA.
europepmc +1 more source
The developmental selector AS1 is an evolutionarily conserved regulator of the plant immune response
Pedro Luiz Nurmberg+6 more
openalex +1 more source
Six1 is a key regulator of the developmental and evolutionary architecture of sensory neurons in craniates [PDF]
Hiroshi Yajima+8 more
openalex +1 more source
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald+18 more
wiley +1 more source
MEF2 transcription factors: developmental regulators and emerging cancer genes. [PDF]
Pon JR, Marra MA.
europepmc +1 more source
Dual developmental role of transcriptional regulator Ets1 in Xenopus cardiac neural crest vs. heart mesoderm [PDF]
Shuyi Nie, Marianne Bronner‐Fraser
openalex +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias+12 more
wiley +1 more source
Caudal, a key developmental regulator, is a DPE-specific transcriptional factor
Tamar Juven‐Gershon+2 more
openalex +1 more source