Results 191 to 200 of about 2,744,821 (349)

Prenatal Developmental Toxicity of ARVIDEX® Herbal Medicine in Albino Wistar Rats. [PDF]

Cureus
Engeu Ogwang P, Joshua K, Katende P, Arisinga TR, Kyomugisha S, Neeza T, Terkimbi SD, Mekuriya Yadesa T, Mwandah DC.   +8 more
europepmc   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

Deciphering epigenetic regulation in cardiac developmental toxicity: Mechanisms and implications (Review). [PDF]

Mol Med Rep
Qin Z, Chen R, Song D.
europepmc   +1 more source

Developmental Toxicity and Thyroid-Disrupting Effects of Combined Exposure to Pb(II) and ²¹⁰Pb(II) in Zebrafish Embryos. [PDF]

Toxics
Xu C, Li Y, Chen L, He L, Xu R, Li T, Niu L, Liu W, Guo Z, Hu C.   +9 more
europepmc   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Incorporation of Selenium into Sol–Gel‐Derived Bioactive Glass: Influence on Glass Structure, Bioactivity, and its Selective Cytotoxicity

Advanced Engineering Materials, EarlyView.
Selenium was incorporated into a sol–gel‐derived bioactive glass to enable sustained therapeutic ion release. The selenium‐containing glass preserved bioactivity while selectively inducing cytotoxicity in osteosarcoma cells and maintaining osteoblastic viability.
Breno Rocha Barrioni, Thalita Marcolan Valverde, Talita Martins, Guilherme Mattos Jardim Costa, Alfredo Miranda de Goes, Marcello Rosa Dumont, Eduardo Henrique Martins Nunes, Marivalda de Magalhães Pereira   +7 more
wiley   +1 more source

Hypothesis-driven approach to developmental toxicity assessment: Using mechanistic information to inform testing. [PDF]

Reprod Toxicol
Daston G, Burbank M, Gautier F, Hales BF, Jamalpoor A, Kanda Y, Makris S, Piersma AH, Powles-Glover N, Sobrian S, Sutherland V, Van Cruchten S, Wange RL, Chen CL.   +13 more
europepmc   +1 more source

Karl Popper and the Mechanisms of Hydrogen Embrittlement

Advanced Engineering Materials, EarlyView.
Representation of the beginning of loss of ductility rather than embrittlement. Small concentrations of hydrogen in a diffusible form within iron are well‐established to harm the mechanical integrity of steels. There are theories that attempt to explain the pernicious role of hydrogen.
H. K. D. H. Bhadeshia
wiley   +1 more source

Application to developmental toxicity testing of a novel method for whole-brain imaging of microglia in zebrafish. [PDF]

Curr Res Toxicol
Yuge M, Koiwa J, Shiromizu T, Wakai E, Migoguchi A, Nishimura Y.   +5 more
europepmc   +1 more source

Direct Metal Deposition of Graphene–Ti28Nb35.4Zr Matrix Composites With Enhanced Mechanical, Corrosion, and Biocompatibility Properties for Bone Implants

Advanced Engineering Materials, EarlyView.
Graphene nanoplatelet (0.1 wt.%) reinforcement significantly enhances the performance of β Ti‐28Nb‐35.4Zr alloy. Grain refinement, reduced water contact angle, and improved surface characteristics promote osteoblast adhesion and complete surface coverage after 7 days.
Khurram Munir, Jixing Lin, Yuncang Li, Li Zhu, Paul F. A. Wright, Cuie Wen   +5 more
wiley   +1 more source