Results 211 to 220 of about 130,891 (267)

Developmental toxicity of pyrethroids

Archives of Toxicology, 2003
A series of studies by Eriksson (1997) has shown persisting changes in neurochemistry and behaviour of mice after administration of very low doses of a range of pesticides to the neonate. Since these studies had all been made in one laboratory and the effects were seen at dose levels which are otherwise without effect, we set out (funded by the ...
Bala Y, Muhammad, Richard D, Verschoyle, David D, Ray   +2 more
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Developmental aspects of neurobehavioural toxicity

Toxicology Letters, 1992
Previous work on the developmental aspects of neurobehavioural toxicity in rats and mice has shown the reliability of a variety of procedures aimed at assessing changes that may have widespread functional consequences, for example: (i) modified Fox batteries to study the maturation of various reflexes and responses after birth, (ii) activity ...
BIGNAMI G, LAVIOLA G, ALLEVA E, CAGIANO R, LACOMBA C, CUOMO, VINCENZO   +5 more
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Developmental Toxicity Prediction

2012
Developmental toxicity may be estimated using commercial and noncommercial software that is already available in the market and/or literature, or models may be built from scratch using both commercial and noncommercial software packages. In this chapter, commonly available software programs that can predict the developmental toxicity of chemicals are ...
Raghuraman, Venkatapathy, Nina Ching Y, Wang   +1 more
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Developmental toxicity of methylamines in mice

Journal of Toxicology and Environmental Health, 1991
Monomethylamine (MMA), dimethylamine (DMA), and trimethylamine (TMA) are endogenous substances as well as metabolites of methyl isocyanate, the chemical involved in the 1984 accident at Bhopal, India. Although methylamines exert several toxic effects including inhibition of protein turnover and oocyte RNA synthesis, their reproductive toxicity has not ...
I, Guest, D R, Varma
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Reproductive and Developmental Toxicity of Phthalates

Journal of Toxicology and Environmental Health, Part B, 2009
The purposes of this review are to (1) evaluate human and experimental evidence for adverse effects on reproduction and development in humans, produced by exposure to phthalates, and (2) identify knowledge gaps as for future studies. The widespread use of phthalates in consumer products leads to ubiquitous and constant exposure of humans to these ...
Lyche, J.L., Gutleb, A.C., Bergman, A., Eriksen, G.S., Murk, A.J., Ropstad, E., Saunders, M., Skaare, J.U.   +7 more
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Developmental Toxicity Study of Dimethylpiperidone

Drug and Chemical Toxicology, 2004
The potential maternal and developmental toxicity of dimethylpiperidone (DMPD) was assessed in rats. Groups of 25 mated female Crl:CD (SD)IGS BR rats were exposed by inhalation (whole-body exposures) for approximately six hours per day over days 7-21 of gestation (G); day 1G was the day of copulation plug detection. The exposure levels were 0, 52, 260,
Susan M, Munley, Arthur J, O'Neill, Deborah L, Tyler, Mark E, Hurtt, Gerald L, Kennedy   +4 more
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Developmental Toxicants Risk Assessment

Pediatrics, 1992
To The Editor.— Because of their physical vulnerability and diminutive stature, infants and children often are assumed by the general public and by some health professionals to be more susceptible to the potential toxic effects of the chemicals found in the environment.
P S, Guzelian, C J, Henry, W H, Farland, S S, Olin   +3 more
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Developmental toxicity of isomalt in rats

Food and Chemical Toxicology, 1989
The sugar replacer isomalt, a 1:1 mixture of the disaccharides glucopyranosylsorbitol and glucopyranosylmannitol, was incorporated in the diet of rats. Female Bay FB:30 rats were adapted to isomalt by feeding them a diet containing a gradually increasing amount of isomalt for several days, prior to mating. Subsequently, they were mated. Isomalt was fed
Waalkens-Berendsen, D.H., Koeter, H.B.W.M., Schluter, G., Renhof, M.   +3 more
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Developmental Toxicity of Engineered Nanomaterials

2017
Abstract Engineering of nanosized particles provides new material properties due to large surface area, design and control of particle shape, and surface coatings. Toxicological properties of nanoparticles may therefore differ from bulk material. Developmental toxicity of nanoparticles may occur due to “traditional” toxicity, relating to specific ...
Hougaard K. S., Campagnolo L., Fadeel B., Gulumian M., Kagan V. E., Moller P., Jacobsen N. R., Savolainen K. M.   +7 more
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Commentary on the Role of Maternal Toxicity on Developmental Toxicity

Birth Defects Research Part B: Developmental and Reproductive Toxicology, 2012
Maternal mammalian toxicity impacts prenatal development, with general systemic maternal toxicity, from reduced weight gain to morbidity, causative for reduced fetal weights/litter and increased fetal variations (especially skeletal)/litter, but not, in the author's opinion, for increased fetal malformations, reduced litter sizes or full litter losses.
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