Results 271 to 280 of about 2,744,821 (349)

PFAS-induced lipidomic dysregulations and their associations with developmental toxicity in zebrafish embryos.

Science of the Total Environment, 2022
Per- and polyfluoroalkyl substances (PFASs) are persistent environmental contaminants, posing developmental toxicity to fish and human. PFAS-induced lipid metabolism disorders were demonstrated using the zebrafish (Danio rerio) embryo model, but the ...
Zhiyi Yang, Lei Fu, Mengxi Cao, Fang Li, Jingguang Li, Zhiyu Chen, Ang Guo, Huifang Zhong, Wenbo Li, Yong Liang, Qian Luo   +10 more
semanticscholar   +1 more source

Reproductive and developmental toxicity of solvents and gases

Reproductive and Developmental Toxicology, 2022
This chapter is focused on the reproductive and developmental toxicity of selected commonly used volatile solvents and gases to which inhalation is a primary route of exposure in humans.
S. Vulimiri, M. Pratt, Shaila Kulkarni, S. Beedanagari, B. Mahadevan   +4 more
semanticscholar   +1 more source

In vivo and in silico evaluations of survival and cardiac developmental toxicity of quinolone antibiotics in zebrafish embryos (Danio rerio).

Environmental Pollution, 2021
Quinolones are ranked as the second most commonly used class of antibiotics in China, despite their adverse clinical and environmental effects. However, information on their cardiac developmental toxicity to zebrafish is limited.
Ying Han, Yuanyuan Ma, S. Yao, Jingpu Zhang, Changqin Hu   +4 more
semanticscholar   +1 more source

Developmental toxicity of pyrethroids

Archives of Toxicology, 2003
A series of studies by Eriksson (1997) has shown persisting changes in neurochemistry and behaviour of mice after administration of very low doses of a range of pesticides to the neonate. Since these studies had all been made in one laboratory and the effects were seen at dose levels which are otherwise without effect, we set out (funded by the ...
Bala Y, Muhammad, Richard D, Verschoyle, David D, Ray   +2 more
openaire   +2 more sources

Developmental aspects of neurobehavioural toxicity

Toxicology Letters, 1992
Previous work on the developmental aspects of neurobehavioural toxicity in rats and mice has shown the reliability of a variety of procedures aimed at assessing changes that may have widespread functional consequences, for example: (i) modified Fox batteries to study the maturation of various reflexes and responses after birth, (ii) activity ...
BIGNAMI G, LAVIOLA G, ALLEVA E, CAGIANO R, LACOMBA C, CUOMO, VINCENZO   +5 more
openaire   +3 more sources

Developmental toxicity of the novel PFOS alternative OBS in developing zebrafish: An emphasis on cilia disruption.

Journal of Hazardous Materials, 2020
In recent years, sodium p-perfluorous nonenoxybenzene sulfonate (OBS) has emerged as a substitute for PFOS with large demand and application in the Chinese market. However, little is known about potential developmental effects of OBS.
Jing Huang, Liwei Sun, J. Mennigen, Yu Liu, Shuai Liu, Miao Zhang, Qiyu Wang, W. Tu   +7 more
semanticscholar   +1 more source

Developmental Toxicity Prediction

2012
Developmental toxicity may be estimated using commercial and noncommercial software that is already available in the market and/or literature, or models may be built from scratch using both commercial and noncommercial software packages. In this chapter, commonly available software programs that can predict the developmental toxicity of chemicals are ...
Raghuraman, Venkatapathy, Nina Ching Y, Wang   +1 more
openaire   +2 more sources

Developmental Toxicity Study of Dimethylpiperidone

Drug and Chemical Toxicology, 2004
The potential maternal and developmental toxicity of dimethylpiperidone (DMPD) was assessed in rats. Groups of 25 mated female Crl:CD (SD)IGS BR rats were exposed by inhalation (whole-body exposures) for approximately six hours per day over days 7-21 of gestation (G); day 1G was the day of copulation plug detection. The exposure levels were 0, 52, 260,
Susan M, Munley, Arthur J, O'Neill, Deborah L, Tyler, Mark E, Hurtt, Gerald L, Kennedy   +4 more
openaire   +2 more sources

A critical review on male-female reproductive and developmental toxicity induced by micro-plastics and nano-plastics through different signaling pathways.

Chemico-Biological Interactions
It is widely accepted that humans are constantly exposed to micro-plastics and nano-plastics through various routes, including inhalation of airborne particles, exposure to dust, and consumption of food and water.
Waseem Ali, R. Buriro, J. Gandahi, Yan Chen, Zain ul Aabdin, Sahar Bhutto, Jian Sun, Jiaqiao Zhu, Zongping Liu, H. Zou   +9 more
semanticscholar   +1 more source

Effects of the chorion on the developmental toxicity of organophosphate esters in zebrafish embryos.

Journal of Hazardous Materials, 2020
Many toxicological studies have utilized zebrafish embryos to investigate the developmental toxicity of organophosphate esters (OPEs). However, in respect of the presence or absence of the chorion, a consistent experimental methodology has yet to be ...
C. M. Tran, Hyojin Lee, Byoung-cheun Lee, J. Ra, Ki-Tae Kim   +4 more
semanticscholar   +1 more source