Results 51 to 60 of about 22,593 (251)

Impacts of Workplace Culture on Deviant Workplace Behavior: A Systematic Review

SAGE Open
Deviant workplace behavior violates organizational standards and has the potential to hurt either the entire organization or specific members of the organization. It is a serious and present problem in the workplace. Workplace culture have been linked to
Muhammad Amin bin Bujang, Mohammad Rahim Kamaluddin, Salawati Mat Basir, Shalini Munusamy, Hee Jhee Jiow   +4 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

The relationship of real-life interpersonal difficulties and Chinese adolescents’ online deviant behavior: a U-shaped mediated moderating effect of online morality

Humanities & Social Sciences Communications
Based on the integrated perspective of reality and virtual networks, this study aims to explore the mechanism of how interpersonal difficulties influence Chinese adolescents’ online deviant behavior and the roles of online morality and online social ...
Yanlei Chen, Shaoyang Guo, Yuanyuan Yu
doaj   +1 more source

A STUDY OF THE «I-CONCEPT» OF SCHOOLCHILDREN WITH DEVIANT BEHAVIOR

Russian Journal of Education and Psychology
Background. Changes in the formation of the «I-concept» can lead to deviant behavior. Deviant behavior of children is a problem, as identification and correction requires a lot of effort. Deviant behavior can manifest itself in different behaviors.
Mikhail I. Kargin, Olga N. Anashkina
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Homosexualité : la formulation d’une perspective sociologique [1967]

Genre, Sexualité et Société, 2011
Homosexuality, as well as other forms of social or sexual deviance, has tended to require special conceptual approaches, approaches that all too often treat non-deviant forms of behavior (e.g., heterosexuality, noncriminal behavior, nonsuicidal behavior,
William Simon, John H. Gagnon
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source