Results 21 to 30 of about 1,183 (212)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

An Integrated Two-Factor Authentication Scheme for Smart Communications and Control Systems

open access: yesMendel, 2023
Fast and reliable authentication is a crucial requirement of communications networks and has various research challenges in an Internet of Things (IoT) environment.
Trong-Minh Hoang   +2 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Low-cost group-based identity security authentication protocol for NB-IoT nodes

open access: yesTongxin xuebao, 2021
To address the problem of huge number of signaling requests when large-scale devices request authentication in NB-IoT network, a low-cost group identity security authentication protocol based on Schnorr aggregate signature and Chinese reminder theorem ...
Xiangmao CHANG, Jun ZHAN, Zhiwei WANG
doaj   +2 more sources

A Study on IoT Device Authentication Using Artificial Intelligence

open access: yesSensors
Designing reliable authentication mechanisms for IoT devices is increasingly necessary to protect citizens’ private information and data. One of the most significant issues in today’s digital age is authentication.
Shahram Miri Kelaniki, Nikos Komninos
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Scalable and CMOS compatible silicon photonic physical unclonable functions for supply chain assurance

open access: yesScientific Reports, 2022
We demonstrate the uniqueness, unclonability and secure authentication of N = 56 physical unclonable functions (PUFs) realized from silicon photonic moiré quasicrystal interferometers.
Farhan Bin Tarik   +3 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Physical Unclonable Function and Hashing Are All You Need to Mutually Authenticate IoT Devices

open access: yesSensors, 2020
Internet of Things (IoT) has become the driving force in modern day technology with an increasing and rapid urge to create an intelligent, efficient, and connected world.
Ahmed Mostafa   +2 more
doaj   +1 more source

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