Results 11 to 20 of about 251,034 (305)

Dexamethasone-(C21-phosphoramide)-[anti-EGFR]: molecular design, synthetic organic chemistry reactions, and antineoplastic cytotoxic potency against pulmonary adenocarcinoma (A549) [PDF]

open access: yesDrug Design, Development and Therapy, 2016
Cody P Coyne,1 Lakshmi Narayanan2 1Department of Basic Sciences, 2Department of Clinical Sciences, College of Veterinary Medicine, Mississippi State University, Starkville, MS, USA Purpose: Corticosteroids are effective in the management of a variety ...
Coyne CP, Narayanan L
doaj   +1 more source

ATOME-MORU/dexamethasone-: Dexamethasone cost effectiveness [PDF]

open access: yes, 2020
Code release accompanying the paper entitled: "The potential health and economic impact of dexamethasone treatment for patients with COVID-19" Authors: Ricardo Águas, Adam Mahdi, Rima Shretta, Peter Horby, Martin Landray, Lisa White, and the CoMo ...
ricardoaguas
core   +1 more source

Prunetin Protects Against Dexamethasone-Induced Pancreatic Β-Cell Apoptosis via Modulation of p53 Signaling Pathway

open access: yesNatural Product Communications, 2020
Long-term administration of dexamethasone results in insulin resistance and pancreatic β-cell apoptosis. Prunetin (an O -methylated isoflavone, a type of flavonoid) is demonstrated to protect diabetes, but the molecular mechanism of this protection is ...
Suwattanee Kooptiwut   +4 more
doaj   +1 more source

The Efficacy of High-Dose Dexamethasone vs. Other Treatments for Newly Diagnosed Immune Thrombocytopenia: A Meta-Analysis

open access: yesFrontiers in Medicine, 2021
Objective: To compare the therapeutic efficacies of high dose dexamethasone, prednisone and rituximab in combination with dexamethasone for newly diagnosed ITP (Immune Thrombocytopenia, ITP) patients.Methods and results: Relevant publications for this ...
Qirong Xiao   +8 more
doaj   +1 more source

Dexamethasone Improves Cardiovascular Outcomes in Critically Ill COVID-19, a Real World Scenario Multicenter Analysis

open access: yesFrontiers in Medicine, 2022
BackgroundSevere COVID-19 pneumonia requiring intensive care treatment remains a clinical challenge to date. Dexamethasone was reported as a promising treatment option, leading to a reduction of mortality rates in severe COVID-19 disease.
Peter Jirak   +18 more
doaj   +1 more source

Analysis of renal impairment in MM-003, a phase III study of pomalidomide + low - dose dexamethasone versus high - dose dexamethasone in refractory or relapsed and refractory multiple myeloma

open access: yesHaematologica, 2016
Pomalidomide + low-dose dexamethasone is effective and well tolerated for refractory or relapsed and refractory multiple myeloma after bortezomib and lenalidomide failure.
Katja C. Weisel   +22 more
doaj   +1 more source

Immune and ionic mechanisms mediating the effect of dexamethasone in severe COVID-19

open access: yesFrontiers in Immunology, 2023
IntroductionSevere COVID-19 is characterized by cytokine storm, an excessive production of proinflammatory cytokines that contributes to acute lung damage and death.
Ameet A. Chimote   +7 more
doaj   +1 more source

Dexamethasone Effect on Sudden Hearing Loss is Validated in Stress-induced Animal Models: Hypothetical Study [PDF]

open access: yes, 2023
BACKGROUND: Stress could be a contributing cause of sudden hearing loss. This study intended to develop an animal model of stress-induced sudden hearing loss and to evaluate the effects of dexamethasone.
Kim, YJ   +15 more
core   +1 more source

Comparison of Intravitreal Bevacizumab Upload Followed by a Dexamethasone Implant versus Dexamethasone Implant Monotherapy for Retinal Vein Occlusion with Macular Edema [PDF]

open access: yes, 2012
Purpose: To compare the efficacy and safety of three intravitreal bevacizumab upload injections followed by a dexamethasone implant versus dexamethasone implant monotherapy in eyes with macular edema due to retinal vein occlusion.
Haritoglou, Christos   +7 more
core   +1 more source

Dexamethasone enhances osteogenic differentiation of bone marrow- and muscle-derived stromal cells and augments ectopic bone formation induced by bone morphogenetic protein-2. [PDF]

open access: yesPLoS ONE, 2015
UNLABELLED:We evaluated whether dexamethasone augments the osteogenic capability of bone marrow-derived stromal cells (BMSCs) and muscle tissue-derived stromal cells (MuSCs), both of which are thought to contribute to ectopic bone formation induced by ...
Masato Yuasa   +10 more
doaj   +1 more source

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