Results 241 to 250 of about 237,941 (312)

Innovations in Dental Implants Integration: Optimizing dental implants performance utilizing stem cells and coatings

Biotechnology Progress, EarlyView.
Abstract The last two decades, between 2000 and 2024, significant steps were achieved regarding the interaction between various stem cells and titanium implant surfaces to improve dental implant integration. This literature review focuses on the potential effects of (i) bone marrow mesenchymal stem cells (BMSCs), (ii) periodontal ligament stem cells ...
Ioannis Tsamesidis, Athanasios Christodoulou, Evangelia Stalika, Georgia K. Pouroutzidou, Eleana Kontonasaki   +4 more
wiley   +1 more source

Evaluation of triply periodic minimal surface geometries in 3D‐printed PLA scaffolds for chondrogenic differentiation

Biotechnology Progress, EarlyView.
Abstract Triply periodic minimal surface (TPMS) scaffolds are gaining attention in tissue engineering due to their continuous and interconnected porous architecture. In this study, three TPMS geometries—Gyroid, Diamond, and I‐WP—were fabricated from polylactic acid (PLA) using fused deposition modeling (FDM), with all scaffolds designed to maintain the
Mahmut Alp Kılıç, Mustafa Akyürek, Roozbeh Abidnejad, Alp Karakoç   +3 more
wiley   +1 more source

Synthesis and Characterization of Dummy Template‐Based Molecularly Imprinted Polymers for Extraction of Aflatoxins in Food Samples

Chemistry &Biodiversity, EarlyView.
Five dummy templates and two functional monomers were systematically evaluated for the preparation of selective MIPs for aflatoxins. 5,7‐Dimethoxycoumarin and methacrylic acid were found to produce highly selective MIPs, and the adsorbent was characterized by FTIR, TGA, and SEM.
Mesha Mbisana, Dikabo Mogopodi, Moses T. Kabomo, Baagi T. Mmereki   +3 more
wiley   +1 more source

Expanding the Phenotype of CYFIP2‐Related Developmental Epileptic Encephalopathy: Case Report and Literature Review

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Background Pathogenic CYFIP2 variants cause developmental and epileptic encephalopathy (DEE), characterized by early‐onset intractable epilepsy and developmental delay. The disease course has not been delineated. Codon Arg87 is a de novo mutational hotspot associated with a severe DEE phenotype via gain‐of‐function mechanisms. Currently, there
Michaela Squire, Jenna K. Lea, Zheng (Jane) Fan, Senyene E. Hunter   +3 more
wiley   +1 more source

<i>Lithospermum erythrorhizon</i> extract alleviates immunosuppression via MAPK signaling pathway. [PDF]

Front Vet Sci
Chi X, Ping L, Gai R, Weng Q.
europepmc   +1 more source

Repurposing Acebutolol for Osteoporosis Treatment: Insights From Multi‐Omics and Multi‐Modal Data Analysis

Clinical Pharmacology &Therapeutics, EarlyView.
Overview of a multi‐omics based drug repurposing strategy. The systematic drug repurposing strategy included the following steps: (1) osteoporosis driver signaling networks were identified from multi‐omics data; (2) drug functional modules were obtained using a network fusion approach to integrate drug similarity information; (3) all drugs were ranked ...
Dan‐Yang Liu, Hui Shen, Jonathan Greenbaum, Qiao‐Rong Yi, Shuang Liang, Yue Zhang, Jia‐Chen Liu, Chuan Qiu, Lan‐Juan Zhao, Qing Tian, Kuan‐Jui Su, Zhe Luo, Li Wu, Xiang‐He Meng, Hong‐Mei Xiao, Yun Deng, Yang Li, Dragana Lovre, Vivian Fonseca, Fernando L. Sanchez, Li‐Jun Tan, Hong‐Wen Deng   +21 more
wiley   +1 more source

Comparison of Perioperative Single-Dose Systemic Dexamethasone Versus Placebo for Prolongation of Postoperative Analgesia in Term Parturients Undergoing Cesarean Section Under Spinal Anesthesia. [PDF]

Cureus
Ravishankar N, Kalingarayar S, Govarthanan S.   +2 more
europepmc   +1 more source

Association Discovery Approach in Healthcare Big Data to Identify Drug Safety and Drug Repurposing Signals

Clinical Pharmacology &Therapeutics, EarlyView.
Data science approaches have been increasingly implemented in healthcare big data to evaluate the safety and effectiveness of drugs. Association discovery is a data mining approach that finds potentially associated elements in high‐dimensional data. We present a novel implementation of the association discovery approach in longitudinal healthcare data ...
George S. Q. Tan, Lynn Miller, Sam Wade, Jenni Ilomäki, Dickson Lukose, Jia Rong, Geoffrey I. Webb   +6 more
wiley   +1 more source

Dexamethasone-eluting cochlear implants reduce inflammation and foreign body response in human and murine cochleae. [PDF]

Sci Rep
Rahman MT, Mostaert BJ, Eckard P, Fatima SM, Scheperle R, Razu I, Hunger B, Olszewski RT, Gu S, Garcia CL, Khan NA, Bennion DM, Oleson J, Kirk JR, Enke YL, Gay RD, Morell RJ, Hirose K, Hoa M, Claussen AD, Hansen MR.   +20 more
europepmc   +1 more source

Clinical Implementation of Pharmacogenomics and Drug–Drug Interaction Screening in a German Academic Teaching Hospital and Outpatient Follow‐Up

Clinical Pharmacology &Therapeutics, EarlyView.
Overview of the implemented pharmacogenomics (PGx) process in clinical routine at the Robert Bosch Hospital: from patient enrollment via the hospital information system, DNA detection using a customized TaqMan OpenArray panel and qPCR for CNV assessment, to clinical translation of genotyping results into PGx guideline‐based recommendations using a ...
Roman Tremmel, Filippa Schreeck, Simon Jaeger, Severin Schricker, Elke Schaeffeler, Svitlana Igel, Daniela Steinberger, Manuel Pagitz, Jörg Latus, Markus Ketteler, Kerstin Bühl, Marc‐H. Dahlke, Hans‐Georg Kopp, Matthias Schwab   +13 more
wiley   +1 more source