Results 101 to 110 of about 63,586 (320)

Emergence of Medetomidine in the Unregulated Drug Supply and Its Association With Hallucinogenic Effects

Drug and Alcohol Review, EarlyView.
ABSTRACT Introduction The unregulated drug supply in the United States is rapidly evolving, and veterinary tranquillisers have emerged as adulterants of concern, especially in illicitly‐manufactured fentanyl. Following the proliferation of xylazine, medetomidine, a more potent sedative, has recently appeared in multiple US states.
Adams L. Sibley, Madigan L. Bedard, Samuel Tobias, Brooke A. Chidgey, Irina G. Phillips, Alice Bell, Nabarun Dasgupta   +6 more
wiley   +1 more source

Bilateral laryngeal paralysis (aplegia) occurring late during the recovery of a horse after orthopaedic surgery

Equine Veterinary Education, EarlyView.
Summary A 9‐year‐old male castrated Standardbred was presented for evaluation of a comminuted right front first phalanx fracture. On initial clinical examination, mild haemoconcentration and increased vital parameters were noted. After overnight hospitalisation, the horse underwent general anaesthesia for surgical fracture repair.
I. Lutvikadic, K. Hopster, B. Driessen
wiley   +1 more source

Highly variable pharmacokinetics of dexmedetomidine during intensive care: a case report

Journal of Medical Case Reports, 2010
Introduction Dexmedetomidine is a selective and potent alpha2-adrenoceptor agonist licensed for use in the sedation of patients initially ventilated in intensive care units at a maximum dose rate of 0.7 μg/kg/h administered for up to 24 hours.
Scheinin Mika, Kurvinen Juha-Pekka, Aantaa Riku, Kentala Erkki, Laitio Ruut, Iirola Timo, Olkkola Klaus T   +6 more
doaj   +1 more source

Pregabalin contributes to increased recovery time from isoflurane anaesthesia for magnetic resonance imaging in horses

Equine Veterinary Journal, EarlyView.
Abstract Background Pregabalin reduces excitatory neurotransmitter release and is used for anxiolysis in humans, cats, and horses. The effects of pregabalin on equine recovery following isoflurane anaesthesia are unknown. Objectives To determine if pre‐anaesthetic oral pregabalin influences recovery time and/or quality from isoflurane anaesthesia in ...
Abigail Blanton, Kati G. Glass, Jeanette Bayer, Courtney Baetge, Ryota Watanabe, Sarah N. Sampson, Mauricio Lépiz, Kara Moreno, Keila K. Ida   +8 more
wiley   +1 more source

Comparison of dexmedetomidine and dexamethasone as adjuvant for ropivacaine in ultrasound-guided erector spinae plane block for video-assisted thoracoscopic lobectomy surgery: a randomized, double-blind, placebo-controlled trial.

Annals of Translational Medicine, 2019
Background Adding an adjuvant, such as dexmedetomidine or dexamethasone, to a nerve block improves its quality and reduces perioperative opioid consumption.
Zhi-xin Gao, Yimin Xiao, Qing Wang, Yuanhai Li   +3 more
semanticscholar   +1 more source

Flow‐controlled expiration improves gas exchange in anaesthetised horses undergoing orthopaedic surgery

Equine Veterinary Journal, EarlyView.
Abstract Background Flow‐controlled expiration (FLEX) has been shown to significantly enhance oxygenation in horses under laboratory conditions. Objective This study aims to corroborate these findings by evaluating the effects of FLEX on gas exchange in a randomised clinical trial involving a large population of clinical horses undergoing orthopaedic ...
Klaus Hopster, Joao Henrique Neves Soares, David Levine, Kyla Ortved, Bernd Driessen, Joaquin Araos   +5 more
wiley   +1 more source

Cone beam computed tomographic myelography in horses with cervical vertebral compressive myelopathy

Equine Veterinary Journal, EarlyView.
Abstract Background While computed tomographic (CT) myelography is increasingly available and has been evaluated in alive horses, objective criteria for diagnosing cervical vertebral compressive myelopathy (CVCM) are lacking. Objectives To establish morphometric dimensions of the cervical vertebral canal and spinal cords from horses with CVCM and ...
Sonia González‐Medina, Myra F. Barrett, Tawfik A. Aboellail, Bradley B. Nelson, Yvette S. Nout‐Lomas   +4 more
wiley   +1 more source

A Neonatal Nurse‐Controlled Model of Analgesia to Manage Post‐Operative Pain in the Surgical Neonate: A Pilot Randomised Controlled Trial

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim To test the feasibility and acceptability of a newly developed model of neonatal nurse‐controlled analgesia to manage pain in the post‐operative infant. Design The study utilised a single‐centre two‐arm parallel, unblinded randomised controlled external pilot trial design.
Renee Muirhead, Kathryn Kynoch, Glenda Hawley, Emma Ballard, Pita Birch, P. A. Lewis   +5 more
wiley   +1 more source

Visualization of Real‐Time Esophageal Location Using Intracardiac Echocardiography on a Three‐Dimensional Mapping System: Comparison of Esophageal Location Using Preoperative Computed Tomography and Investigation of Predictors for Esophageal Movement During Catheter Ablation

Journal of Cardiovascular Electrophysiology, EarlyView.
Esophageal imaging using intracardiac echocardiography (ICE‐Eso) showed a more accurate real‐time esophageal location than preoperative computed tomography (CT‐Eso). Non‐fasting on the day of catheter ablation (CA) may be a predictor of esophageal movement on the day of CA.
Koji Sudo, Kenji Kuroki, Chisa Asahina, Maoko Atsumi, Kazuya Nakagawa, Tetsuya Asakawa, Tomoaki Hasegawa, Kazutaka Aonuma, Akira Sato   +8 more
wiley   +1 more source

Molecular mechanism for pancreatic β‐cell dysfunction and atherosclerosis and its therapeutic application: Importance of translational research bridging clinical practice and basic research

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Introduction It is well‐known that when pancreatic β‐cells are chronically exposed to hyperglycemia under diabetic conditions, β‐cell function is gradually deteriorating. Although such phenomena were well‐known as β‐cell glucose toxicity in clinical practice, its molecular mechanism remained unknown.
Hideaki Kaneto, Tomohiko Kimura, Junpei Sanada, Yuichiro Iwamoto, Masashi Shimoda, Shuhei Nakanishi, Kohei Kaku   +6 more
wiley   +1 more source