Results 81 to 90 of about 69,499 (314)

Pharmacological treatment strategies to manage precipitated withdrawal following the administration of buprenorphine in opioid use disorder: A systematic review

open access: yesAddiction, EarlyView.
Abstract Background and aims There has been limited evidence synthesis examining the treatment of buprenorphine precipitated opioid withdrawal (BPOW). We aimed to conduct the first systematic review to assess the clinical utility of any pharmacological intervention in the management of BPOW.
Emmert Roberts, Nicola Kalk, John Strang
wiley   +1 more source

A loading dose of 1 μg/kg and maintenance dose of 0.5 μg/kg/h of dexmedetomidine for sedation under spinal anesthesia may induce excessive sedation and airway obstruction [PDF]

open access: yes, 2016
Background: For many drugs, dosing scalars such as ideal body weight (IBW) and lean body mass are recommended over the use of total body weight (TBW) during weight-based dose calculations. Doses based on TBW are frequently used, and this may cause under-
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core   +1 more source

Interventions to prevent postoperative neurocognitive complications: an umbrella review of meta‐analyses of randomised controlled trials

open access: yesAnaesthesia, EarlyView.
Summary Introduction The certainty of the effectiveness of interventions to manage postoperative neurocognitive complications remains unclear. The objective of this umbrella review was to synthesise and evaluate the evidence for interventions aimed at reducing the incidence of peri‐operative neurocognitive complications.
Filippo D'Amico   +7 more
wiley   +1 more source

41. The myocardial protective effect of dexmedetomidine in high risk patients undergoing aortic vascular surgery

open access: yesJournal of the Saudi Heart Association, 2016
Dexmedetomidine provides perioperative cardiac protection in high risk patients assessment the effect of dexmedetomidine in high risk patients undergoing aortic vascular surgery. Arandomized study included 150 patients classified into two groups(n = 75).
R. Soliman
doaj   +1 more source

Artificial intelligence‐assisted tracheal intubation in humans: a prospective observational study of diagnostic accuracy

open access: yesAnaesthesia, EarlyView.
Summary Introduction larynGuide™ is a novel assistive software integrated with the C‐MAC® videolaryngoscope, which provides guidance during laryngoscopy and advises on tracheal tube position. This first in‐human study evaluated the accuracy and reliability of larynGuide compared with the judgment of the airway operator. Methods This prospective, single‐
Alexander Fuchs   +7 more
wiley   +1 more source

Prevalence and Risk Factors for Upper Airway Obstruction after Pediatric Cardiac Surgery [PDF]

open access: yes, 2015
Objective To determine the prevalence of and risk factors for extrathoracic upper-airway obstruction after pediatric cardiac surgery. Study design A retrospective chart review was performed on 213 patients younger than 18 years of age who recovered ...
Delius, Ralph E.   +4 more
core   +1 more source

Opioid‐free vs. opioid‐inclusive anaesthesia with or without regional anaesthesia for postoperative pain: a systematic review with network meta‐analysis of randomised controlled trials

open access: yesAnaesthesia, EarlyView.
Summary Introduction Concerns about opioid‐related adverse effects have increased interest in opioid‐free anaesthesia, but the benefits compared with opioid‐inclusive techniques, especially in the presence of regional anaesthesia, remain uncertain. Methods We undertook a systematic review with a network meta‐analysis of randomised controlled trials ...
Clístenes C. de Carvalho   +11 more
wiley   +1 more source

Symptomatic treatment of children with anti-NMDAR encephalitis. [PDF]

open access: yes, 2016
AIM: We performed the first study on the perceived benefit and adverse effects of symptomatic management in children with anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis.
Brilot, F   +7 more
core   +1 more source

Pharmacological inhibition of hydroxysteroid 11‐beta dehydrogenase type 1 (11‐βHSD1) after myocardial infarction preserves cardiac function in a translational mini‐pig model

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Plasma glucocorticoids increase acutely after MI, thereafter tissue levels are amplified selectively within cells expressing 11‐ßhydroxysteroid dehydrogenase type 1 (11‐ßHSD1) that regenerates active glucocorticoids from circulating metabolites.
Sara Al Disi   +19 more
wiley   +1 more source

The influence of subanaesthetic ketamine on regional cerebral blood flow in healthy dogs measured with 99mTc-HMPAO SPECT [PDF]

open access: yes, 2018
Subanaesthetic ketamine has recently been proven to be a highly effective and fast acting alternative treatment for several psychiatric disorders. The mechanisms responsible for ketamine's antidepressant effects remain unclear, but a possible explanation
Audenaert, Kurt   +7 more
core   +3 more sources

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