Results 81 to 90 of about 65,011 (307)

Update on dexmedetomidine: use in nonintubated patients requiring sedation for surgical procedures

Therapeutics and Clinical Risk Management, 2010
Mohanad Shukry, Jeffrey A MillerUniversity of Oklahoma Health Sciences Center, Department of Anesthesiology, Children’s Hospital of Oklahoma, Oklahoma City, OK, USAAbstract: Dexmedetomidine was introduced two decades ago as a sedative and ...
Mohanad Shukry, Jeffrey A Miller
doaj  

Is there a place for dexmedetomidine in equine anaesthesia and analgesia? : a systematic review (2005-2017) [PDF]

, 2018
The objective of this review was to perform a literature compilation of all the equine publications that used dexmedetomidine as the first article on this topic was published, in 2005.
Ambrisko, Ansah, Benmansour, Benmansour, Benmansour, Bettschart-Wolfensberger, Bettschart-Wolfensberger, Bettschart-Wolfensberger, Bettschart-Wolfensberger, De Clercq, Devisscher, Duke-Novakovski, Enderle, Gozalo-Marcilla, Gozalo-Marcilla, Gozalo-Marcilla, Gozalo-Marcilla, Gozalo-Marcilla, Grimsrud, Grimsrud, Grimsrud, Guedes, Hopster, Johnston, Kalchofner, Kharasch, Knych, Kuusela, Lizarraga, Lizarraga, Marcilla, Marcilla, Marly-Voquer, Müller, Pöppel, Ranheim, Rezende, Risberg, Risberg, Sacks, Santos, Savola, Schauvliege, Segal, Taylor, Wojtasiak-Wypart   +45 more
core   +2 more sources

Dexmedetomidine as a Ropivacaine Adjuvant in a Thoracic Paravertebral Block Combined With an Erector Spinae Plane Block for Improving Early Quality of Recovery After Transapical Transcatheter Aortic Valve Implantation

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT The study aimed to investigate the effectiveness of dexmedetomidine (Dex) as an adjuvant for ropivacaine in a thoracic paravertebral block (TPVB) combined with an erector spinae plane block (ESPB) for improving early quality of recovery and postoperative pain after transapical transcatheter aortic valve implantation (TAVI).
Gui‐Ling Dong, Rong‐En Qiu, Chen‐Zhan Xu   +2 more
wiley   +1 more source

The antioxidant effect of preischemic dexmedetomidine in a rat model: increased expression of Nrf2/HO-1 via the PKC pathway

Brazilian Journal of Anesthesiology, 2023
Background: The precise underlying mechanism of antioxidant effects of dexmedetomidine-induced neuroprotection against cerebral ischemia has not yet been fully elucidated.
Yong-Hee Park, Hee-Pyoung Park, Eugene Kim, Hannah Lee, Jung-Won Hwang, Young-Tae Jeon, Young-Jin Lim   +6 more
doaj  

Dexmedetomidine in the Supratentorial Craniotomy

The Eurasian Journal of Medicine, 2010
In this double-blind prospective clinical study, we investigated the effects of fentanyl and dexmedetomidine as adjuvant agents in supratentorial craniotomies on the following: hemodynamic changes during perioperative and recovery periods, brain edema perioperatively, recovery times and side effects, such as hypertension, shivering, nausea and vomiting.
Senem Koruk, Osman Ilhan, Gokcen Serin, Ibrahim Erkutlu, Unsal Oner   +4 more
openaire   +3 more sources

Dexmedetomidine Prevents Lipopolysaccharide-Induced MicroRNA Expression in the Adult Rat Brain [PDF]

, 2017
During surgery or infection, peripheral inflammation can lead to neuroinflammation, which is associated with cognitive impairment, neurodegeneration, and several neurodegenerative diseases.
Endesfelder, Stefanie, Paeschke, Nadine, Sifringer, Marco, Spies, Claudia D., von Haefen, Clarissa   +4 more
core   +2 more sources

A comprehensive review on adaptive plasticity and recovery mechanisms post‐acquired brain injury

Neuroprotection, EarlyView.
This figure illustrates the dynamic process of neurogenesis following brain injury, focusing on the roles of neural stem and progenitor cells at the injury site. Key mechanisms include axonal sprouting, synaptogenesis, dendritic remodeling, and brain‐derived neurotrophic factor signaling via TrkB receptors.
Ravi Kumar Rajan
wiley   +1 more source

Unveiling the Therapeutic Potential of Atractylis aristata Batt. Aqueous Extract: Anti‐inflammatory, Antioxidant, Antibacterial, Sedative Activities & Phytochemical Profiling

ChemistryOpen, EarlyView.
This study evaluates the pharmacological properties of the aqueous extract of Atractylis aristata, focusing on its antioxidant, anti‐inflammatory, antibacterial, and sedative activities. Phytochemical analysis identifies bioactive compounds, while in vitro and in vivo tests demonstrate its therapeutic potential in addressing oxidative stress ...
Asma Abid, Nourelhouda Mekhadmi, Randa Mlik, Assia Bentahar, Kamilia Bireche, Bariza Frih, Walid Boussebaa, Aicha Mouane, Nezar Cherrada, Ana Sanches Silva, Messaouda Dekmouche, Lazhar Bechki, Khalid Mashay Al‐Anazi, Mohammad Abul Farah, Ahmad Ali   +14 more
wiley   +1 more source

The Effects of Dexmedetomidine on Postoperative Delirium in Adult Cardiac Surgical Patients: A Bayesian Meta-Analysis and Trial Sequential Analysis. [PDF]

Acta Anaesthesiol Scand
ABSTRACT Background An acute episode of delirium among adults following cardiac surgery is associated with increased length of stay in intensive care, prolonged mechanical ventilation, and increased risk of mortality. This robust systematic review with Bayesian meta‐analysis, including trial sequential analysis, has been undertaken to explore the use ...
Keith N, Harrowell L, Alexandrou E, Aneman A, Frost SA.   +4 more
europepmc   +2 more sources

Reducing General Anesthesia for Lumbar Punctures in Pediatric Patients With Leukemia and Lymphoma, a Quality Improvement Project

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Curative therapy for most children with leukemia and lymphoma includes multiple lumbar punctures (LPs) for the administration of intrathecal chemotherapy, commonly facilitated with deep sedation or general anesthesia (GA). There is ongoing concern about the potential for neurocognitive deficits induced by GA in the developing brain ...
Karen Arane, Daphne Li, Tara Baxter, Bina Gandhi, Karyn Positano, Melissa Howlett, Tobias Everett, Sarah Alexander   +7 more
wiley   +1 more source