Results 111 to 120 of about 205,279 (257)

Conjugation of metronidazole with dextran: a potential pharmaceutical strategy to control colonic distribution of the anti-amebic drug susceptible to metabolism by colonic microbes

, 2017
Wooseong Kim, Yejin Yang, Dohoon Kim, Seongkeun Jeong, Jin-Wook Yoo, Jeong-Hyun Yoon, Yunjin Jung Laboratory of Biomedicinal Chemistry, Department of Manufacturing Pharmacy, College of Pharmacy, Pusan National University, Busan, Republic of Korea ...
Kim D, Yang Y, Kim W, Jeong S, Jung Y, Yoo J, Yoon JH   +6 more
core  

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

Advanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao, Yiming Ma, Baihao Shao, Molly M. Stevens   +3 more
wiley   +1 more source

Pullulan–dextran composite beads as bone fillers: from material design and industrial production to clinical application in oral surgery

Frontiers in Bioengineering and Biotechnology
Developing biomaterials from natural polysaccharides for medical applications presents significant challenges in terms of biocompatibility, scalability, and regulatory compliance.
Sylvain Catros, Sylvain Catros, Laurent Bidault, Sandrine Auget, Charlotte Pasquet, Camille Ehret, Rachida Aid, Mathilde Fenelon, Mathilde Fenelon, Jean-Christophe Fricain, Jean-Christophe Fricain, Joelle Amedee-Vilamitjana, Didier Letourneur   +12 more
doaj   +1 more source

A Monolithic Janus Hydrogel Pressure Sensor for Wearable Motion and Physiological Monitoring

Advanced Science, EarlyView.
This work reports a monolithic Janus hydrogel pressure sensor featuring integrated conductive PEDOT and insulating PEGDA layers. The fabricated device achieves a rapid response time, a wide operating range, and good cyclic durability. The sensor demonstrates robust performance in tracking dynamic human joint motions, offering a scalable strategy for ...
Syed Atif Ali, Zeeshan Alam Ansari, Reynaldo Carlos Kuizon Montalbo, Hailemichael Ayalew, Yu‐Sheng Hsiao, Chih‐Wei Chu, Hsiao‐hua Yu, Hsiung‐Lin Tu   +7 more
wiley   +1 more source

Cationized dextran nanoparticle-encapsulated CXCR4-siRNA enhanced correlation between CXCR4 expression and serum alkaline phosphatase in a mouse model of colorectal cancer

, 2012
Fatemeh Abedini,1 Hossein Hosseinkhani,2 Maznah Ismail,1,3 Abraham J Domb,4 Abdul Rahman Omar,1,5 Pei Pei Chong,1,2 Po-Da Hong,3 Dah-Shyong Yu,6 Ira-Yudovin Farber41Laboratory of Molecular Biomedicine, Institute of Bioscience, Universiti Putra Malaysia ...
Abedini F, Chong PP, Ismail M, Omar AR, Farber IY, Hosseinkhani H, Domb AJ, Yu DS, Hong PD   +8 more
core  

Heat‐Suppressing Projection Two‐Photon Lithography Enables High‐Throughput Sub‐Micrometer Manufacturing of Biopolymer Hydrogels for Tissue Engineering

Advanced Science, EarlyView.
The iLEAP technique integrates high‐throughput two‐photon lithography with extrusion printing, bridging sub‐micrometer precision and macroscopic scaffold fabrication. By employing a low‐exothermic photoinitiator, it mitigates thermal damage to biopolymers and preserves bioactivity.
Qifeng Guan, Yanzhe Fu, Xiangyu Xu, Naitao Li, Sen Hou, Kai Wang, Yufan Wang, Jiakun Li, Ping Li, Jiebo Li, Lizhen Wang, Yubo Fan   +11 more
wiley   +1 more source

Biomedical Hydrogel Bio-Adhesive Based on Lactobionic Acid Conjugated Polyethylenimine and Oxidized Dextran with Antioxidant Activity and Cytocompatibility

Pharmaceutics
Background/Objectives: Tissue bio-adhesives have gained significant attention as efficient alternatives to conventional wound closures, which are often hindered by insufficient adhesion and poor biocompatibility.
Lei Nie, Xiaoran Hu, Shichang Cheng, Yingying Liang, Ling Wang, Wei Guo   +5 more
doaj   +1 more source

Regulating Cells Fate and Function to Facilitate Bone Regeneration via Designing Programmable Bio‐Interactive Materials

Advanced Science, EarlyView.
This article aims to elucidate the biological mechanisms of bone repair and the evolution of material design, highlighting key cellular and molecular processes. It further proposes strategies and prospects for programmable bio‐interactive materials, which enable precisely guided bone tissue regeneration by dynamically regulating cell behavior and the ...
Qingrui Fan, Fuming Cao, Junqiang Mao, Pengbin Yin, Licheng Zhang, Jianjun Wang, Peifu Tang   +6 more
wiley   +1 more source

Biodegradable dextran vesicles for effective haemoglobin encapsulation

, 2015
Biodegradable dextran vesicles were developed based on dextran and poly(L-lactide) (PLA). The amphiphilic graft copolymer dextran-g-poly(L-lactide) (dextran-g-PLA) was obtained by coupling carboxyl-terminated PLA to dextran.
Jing,Xiabin, Xie,Zhigang, Huang,Yubin, Liu,Shi, Wang,Weiqi   +4 more
core  

Covalently Linked Peptides and Membrane Potential Enable CyaA Segment Translocation

Advanced Science, EarlyView.
Using a newly developed Droplet Interface Bilayer‐Pipette assay, the authors show that two segments of the CyaA toxin cross membranes by distinct mechanisms. One segment translocates spontaneously, whereas the translocation of the other depends on membrane potential.
Gaia Scilironi, Nicolas Carvalho, Jacinthe Frangieh, Corentin Léger, Dorothée Raoux‐Barbot, J. Iñaki Guijarro, Daniel Ladant, Sophie Cribier, Nicolas Rodriguez, Alexandre Chenal   +9 more
wiley   +1 more source