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Insulin containing polyethylenimine–dextran sulfate nanoparticles

International Journal of Pharmaceutics, 2003
An aqueous nanoparticle delivery system has been developed which employs the oppositely charged polymers polyethylenimine (PEI) and dextran sulfate (DS) with zinc as a stabilizer. It is found that the pH of PEI solutions, the weight ratio of the two polymers, and zinc sulfate concentrations all play significant roles in controlling particle size ...
Waree, Tiyaboonchai   +3 more
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Dextran sulfate disposition in the rat

Biopharmaceutics & Drug Disposition, 1990
AbstractComparative studies of oral and intravenous administration of tritiated dextran sulfate in rats showed markedly different distribution patterns. Following IV dosing about 50 per cent of the radioactivity was recovered in feces and urine within 24 h.
B C, Foster   +4 more
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Characterization of Dextran‐Sulfate‐Sensitive Cells

Scandinavian Journal of Immunology, 1976
The cell type participating in the mitotic response to the polyclonal B‐cell activator (PBA) dextran‐sulfate (DS) was investigated. Cells from murine fetal liver, adult bone marrow, and spleen were studied; only a limited number of all cells present in each organ responded to DS.
E, Gronowicz   +3 more
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Stimulation of extramedullary hemopoiesis by dextran sulfate

Blut, 1983
The spleen of normal dogs (beagles) shows only slight hemopoietic activity, characterized by the presence of megakaryocytes in mitosis and small groups of erythroblasts scattered throughout the red pulp of the organ. Repeated intravenous injection of dextran sulfate, at a dose of 15 mg per kg body weight, produced markedly enhanced erythropoietic and ...
W, Calvo, W M, Ross, T M, Fliedner
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A Novel Method for Differentiating Dextran Sulfate from Related Sulfated Polysaccharides

Journal of Pharmaceutical Sciences, 1991
A method is described for unequivocal identification of dextran sulfate, based on combined chemical desulfation and dextranase enzymolysis of dextran sulfate moieties to isomaltose, a specific indicator of dextran-type precursors. The method was developed using high-resolution (300 MHz) 1H NMR spectroscopy for assurance of the molecular transformations,
K G, Ludwig-Baxter   +3 more
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Rheological behaviour of dextran sulfate solutions

International Journal of Food Engineering, 2012
Abstract The purpose of this research was to study the rheological behaviour of dextran sulfate solutions under different conditions. A PC controlled rotational viscometer with a cone and plate geometry equipped with a temperature controlled unit was used to measure apparent viscosity of dextran solutions at different temperatures (25 ...
Asgar Farahnaky   +5 more
openaire   +1 more source

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