This paper introduces a single‐channel H‐junction microfluidic assay that profiles fibrin's evolving function in repair and thrombosis by measuring, in one ∼3 µL gel, permeability, fibrinolysis kinetics, fibroblast invasion, and clot extension in real time.
Halston Deal +9 more
wiley +1 more source
<i>Parabacteroides goldsteinii</i> Alleviates Intestinal Inflammation in Dextran Sulfate Sodium-Treated Pigs. [PDF]
Deng X +6 more
europepmc +1 more source
Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin +11 more
wiley +1 more source
Cordycepin Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice by Inhibiting IL-6/IL-6R-Mediated p38 MAPK and NF-κB Activation Through Adenosine A<sub>2A</sub> Receptor Stimulation. [PDF]
Liao Y +8 more
europepmc +1 more source
Adhesion‐Related Macrophages Regulate Metabolic Homeostasis Through CAV‐1 Dependency
Adipose tissue harbors a distinct macrophage subpopulation, termed adhesion‐related macrophages (ARMs), which stably adhere to adipocytes. In obesity, ARMs represent the major expanding macrophage subset. They acquire material from adipocytes and rely on Caveolin‐1 for sustained lipid handling.
Wanyu Hu +23 more
wiley +1 more source
Mechanical Stability of Lipid Membranes Decorated with Dextran Sulfate
Candelaria I. Cámara +3 more
doaj +1 more source
The Human Oral Microbial Consortium Associated With Periodontitis Attenuates Weight Loss in Dextran Sulfate Sodium-Induced Colitis. [PDF]
Ikeda E, Yamaguchi M, Kawabata S.
europepmc +1 more source
This study identifies vacuole membrane protein 1 (VMP1) as a critical regulator of intestinal epithelial barrier homeostasis. VMP1 facilitates the recruitment of CORO1C to late endosomes, supporting Retromer‐mediated recycling of the tight junction protein Occludin.
Jiawei Zhao +12 more
wiley +1 more source
Indirubin regulates M1/M2 polarization and inhibits ferroptosis in dextran sulfate sodium induced colitis and in cultured THP-1 cells. [PDF]
Huang YX +10 more
europepmc +1 more source

